SynthesisEuropean journal of clinical nutrition2020
Effect of probiotics and synbiotics on selected anthropometric and biochemical measures in women with polycystic ovary syndrome: a systematic review and meta-analysis.
Synthesis in European journal of clinical nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 6 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Pooled it
- The effects of prebiotic, probiotic or synbiotic supplementation on overweight/obesity indicators: an umbrella review of the trials' meta-analyses.Frontiers in endocrinology · 2024Pooled it
- The role of probiotic supplementation in inflammatory biomarkers in adults: an umbrella meta-analysis of randomized controlled trials.Inflammopharmacology · 2023Pooled it
- The effects of pro-, pre-, and synbiotics supplementation on polycystic ovary syndrome: an umbrella review of meta-analyses of randomized controlled trials.Frontiers in nutrition · 2023Pooled it
- The effects of probiotics, prebiotics, and synbiotics on polycystic ovarian syndrome: an overview of systematic reviews.Frontiers in medicine · 2023Pooled it
- Improvement of glucose metabolism in pregnant women through probiotic supplementation depends on gestational diabetes status: meta-analysis.Scientific reports · 2020Pooled it
- The effect of synbiotics supplementation on anthropometric indicators and lipid profiles in women with polycystic ovary syndrome: a randomized controlled trial.Lipids in health and disease · 2020Trial
- Impact of Reducing Obesity in PCOS: Methods and Treatment Outcomes.Journal of personalized medicine · 2025Review
- The effect of probiotics, prebiotics and synbiotics on gut microbial community profile in overweight and obese Latin American and Caribbean populations: a systematic review of human trials.Gut microbiome (Cambridge, England) · 2025Review
- Inulin-type fructans with different degrees of polymerization improve insulin resistance, metabolic parameters, and hormonal status in overweight and obese women with polycystic ovary syndrome: A randomized double-blind, placebo-controlled clinical trial.Food science & nutrition · 2024Article
- Dietary supplements in polycystic ovary syndrome-current evidence.Frontiers in endocrinology · 2024Review
- Efficacy of Metformin-Cabergoline Compared to Metformin Monotherapy for Management of PCOS With Hyperprolactinemia: A Systematic Review and Meta-analysis.Clinical medicine insights. Endocrinology and diabetes · 2024Article
- Alleviation of Limosilactobacillus reuteri in polycystic ovary syndrome protects against circadian dysrhythmia-induced dyslipidemia via capric acid and GALR1 signaling.NPJ biofilms and microbiomes · 2023Article
- Association of probiotic ingestion with serum sex steroid hormones among pre- and postmenopausal women from the NHANES, 2013-2016.PloS one · 2023Observational
- A narrative review of the role of gastrointestinal dysbiosis in the pathogenesis of polycystic ovary syndrome.Obstetrics & gynecology science · 2022Article
- Probiotics as a Complementary Therapy for Management of Obesity: A Systematic Review.Evidence-based complementary and alternative medicine : eCAM · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to systematically review randomized clinical trials (RCTs) to clarify the effects of pro-/synbiotic supplementation on anthropometric and biochemical measurements in women with polycystic ovary syndrome (PCOS). PubMed, Scopus, ISI Web of Science, Cochrane Library, and Google Scholar were searched through September 2018. Eight RCTs (nine treatment arms) were included. Pro-/synbiotic supplementation significantly reduced fasting blood sugar (-2.52 mg/dl, 95% confidence interval (CI): -4.10 to -0.95), insulin (-2.27 µIU/mL, 95% CI: -3.40 to -1.14), homeostasis model assessment for insulin resistance index (-0.69, 95% CI: -0.98 to -0.40), C-reactive protein (-1.69 Hedges', 95% CI: -3.00 to -0.38), and total testosterone (-0.12 ng/mL, 95% CI: -0.17 to -0.08) in women with PCOS. However, changes in the mean difference of weight and body mass index did not reach a statistically significant level. The findings suggest that pro-/synbiotic supplementation may improve glucose homeostasis parameters, hormonal, and inflammatory indices in women with PCOS.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.