Evidence mapPaperPMID 31055780Full record

ArticleDiabetes therapy : research, treatment and education of diabetes and related disorders2019

Change in HbA

Raffaella Gentilella, Irene Romera, Claudia Nicolay, Raffaella Buzzetti, Luis Alberto Vázquez, Giorgio Sesti

Abstract read
In one paragraph

Article in Diabetes therapy : research, treatment and education of diabetes and related disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  7. Observational
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Raffaella GentilellaEli Lilly Italia, Sesto Fiorentino, Florence, Italy.
Irene RomeraEli Lilly and Company, Alcobendas, Madrid, Spain. romera_irene@lilly.com.
Claudia NicolayLilly Deutschland GmbH, Bad Homburg, Germany.
Raffaella BuzzettiDepartment of Experimental Medicine "Sapienza", University of Rome, Rome, Italy.
Luis Alberto VázquezHospital Marqués de Valdecilla, Santander, Spain.
Giorgio SestiUniversity Magna Graecia, Catanzaro, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis exploratory post hoc analysis investigated the relative changes in glycated haemoglobin (HbA

methodsData from patients receiving once-weekly dulaglutide 0.75 and 1.5 mg, once-daily sitagliptin 100 mg, once-daily liraglutide 1.8 mg or twice-daily exenatide 10 μg in the intent-to-treat populations in the AWARD-5, AWARD-6 and AWARD-1 trials were analysed using last observation carried forward analysis of covariance. Starting with the predefined statistical model from each study, the type of association between HbA

resultsImprovements in HbA

conclusionOur results suggest that dulaglutide is an appropriate therapeutic option for patients with T2DM across a wide range of baseline HbA

fundingEli Lilly and Company. Plain language summary available for this article.

Indexed as

DulaglutideHbA1cIncretin-based therapyRange metabolic controlType 2 diabetes mellitus

Identifiers

PMID31055780
PMCPMC6531505

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.