Evidence map›Paper›PMID 31063008›Full record

ArticleJournal of computational biology : a journal of computational molecular cell biology2019

Causal Gene Regulatory Network Modeling and Genomics: Second-Generation Challenges.

Ellen V Rothenberg

Abstract read
In one paragraph

Article in Journal of computational biology : a journal of computational molecular cell biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Lineage-Selective Dependencies in Pediatric Cancers.Cold Spring Harbor perspectives in medicine · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Proteomic/transcriptomic analysis of erythropoiesis.Current opinion in hematology · 2021
    Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Ellen V RothenbergDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, California.

Funding

Kinetic modeling and single-cell molecular mechanisms of early T-cell commitmentR01HL119102 · NHLBI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI PETERSON, CARSTEN, ROTHENBERG, ELLEN V. · 2014 to 2018
$3.0M
Genomic site binding rules and regulatory factor function in developing T cellsR01HD076915 · NICHD · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ROTHENBERG, ELLEN V. · 2013 to 2017
$2.5M
Key nodes in the T-cell developmental gene regulatory networkR01AI095943 · NIAID · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ROTHENBERG, ELLEN V. · 2011 to 2015
$2.0M
NHLBI NIH HHS R01 HL119102NIAID NIH HHS R01 AI095943NICHD NIH HHS R01 HD076915
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Regulatory NetworksGenomicsModels, GeneticAnimalsChromatinEmbryonic DevelopmentGene Expression Regulation, DevelopmentalChromatindevelopmental kineticsdevelopmental regulationepigenetic constraintgene silencing and de-repressionmodeling causality

Identifiers

PMID31063008
PMCPMC6661971

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.