Evidence map›Paper›PMID 31067416›Full record

ReviewAnnual review of clinical psychology2019

An Active Inference Approach to Interoceptive Psychopathology.

Martin P Paulus, Justin S Feinstein, Sahib S Khalsa

Abstract readReview
In one paragraph

Review in Annual review of clinical psychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 134 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
134citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

134 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Heartbeat-evoked neural response abnormalities in generalized anxiety disorder during peripheral adrenergic stimulation.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
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  9. Review
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  11. Article
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  13. Active inference and speech motor control.Psychonomic bulletin & review · 2026
    Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

74 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Martin P PaulusLaureate Institute for Brain Research, Tulsa, Oklahoma 74136, USA; email: mpaulus@laureateinstitute.org.
Justin S FeinsteinLaureate Institute for Brain Research, Tulsa, Oklahoma 74136, USA; email: mpaulus@laureateinstitute.org.
Sahib S KhalsaLaureate Institute for Brain Research, Tulsa, Oklahoma 74136, USA; email: mpaulus@laureateinstitute.org.

Funding

The Center for Neuroscience-based Mental Health Assessment and Prediction (NEUROMAP)P20GM121312 · NIGMS · LAUREATE INSTITUTE FOR BRAIN RESEARCH · PI Maëlle Camille Marie Gueguen · 2017 to 2026
$23.7M
Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia NervosaK23MH112949 · NIMH · LAUREATE INSTITUTE FOR BRAIN RESEARCH · PI KHALSA, SAHIB · 2017 to 2021
$994k
Investigating Flotation-REST as a novel technique for reducing anxiety and depressionR34AT009889 · NCCIH · LAUREATE INSTITUTE FOR BRAIN RESEARCH · PI KHALSA, SAHIB · 2018 to 2020
$728k
NCCIH NIH HHS R34 AT009889NIGMS NIH HHS P20 GM121312NIMH NIH HHS K23 MH112949
6 · The paper itself

Abstract

Interoception refers to the process by which the nervous system senses and integrates signals originating from within the body, providing a momentary mapping of the body's internal landscape and its relationship to the outside world. Active inference is based on the premise that afferent sensory input to the brain is constantly shaped and modified by prior expectations. In this review we propose that interoceptive psychopathology results from two primary interoceptive dysfunctions: First, individuals have abnormally strong expectations of the situations that elicit bodily change (i.e., hyperprecise priors), and second, they have great difficulty adjusting these expectations when the environment changes (i.e., context rigidity). Here we discuss how these dysfunctions potentially manifest in mental illness and how interventions aimed at altering interoceptive processing can help the brain create a more realistic model of its internal state.

Indexed as

BrainImplosive TherapyInteroceptionMental DisordersMindfulnessModels, TheoreticalPerceptual DisordersHumansanxietycomputational psychiatrydepressioninteroceptionmental healthpredictive coding

Identifiers

PMID31067416
PMCPMC7280559

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.