Evidence map›Paper›PMID 31070384›Full record

ArticleNeuropsychology2019

Types of errors on a semantic interference task in mild cognitive impairment and dementia.

Valeria L Torres, Mónica Rosselli, David A Loewenstein, Rosie E Curiel, Idaly Vélez Uribe, Merike Lang, Fernanda Arruda, Ailyn Penate, David E Vaillancourt, Maria T Greig and 3 more

Abstract read
In one paragraph

Article in Neuropsychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Cross-cultural Diagnostic Validity of the Multilingual Naming Test (MINT) in a Sample of Older Adults.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Salient Cognitive Paradigms to Assess Preclinical Alzheimer's Disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Valeria L Torres1Florida Alzheimer's Disease Research Center.
Mónica Rosselli1Florida Alzheimer's Disease Research Center.
David A Loewenstein1Florida Alzheimer's Disease Research Center.
Rosie E Curiel1Florida Alzheimer's Disease Research Center.
Idaly Vélez Uribe1Florida Alzheimer's Disease Research Center.
Merike Lang1Florida Alzheimer's Disease Research Center.
Fernanda Arruda1Florida Alzheimer's Disease Research Center.
Ailyn PenateMount Sinai Medical Center.
David E Vaillancourt1Florida Alzheimer's Disease Research Center.
Maria T Greig1Florida Alzheimer's Disease Research Center.
William W Barker1Florida Alzheimer's Disease Research Center.
Russell M Bauer1Florida Alzheimer's Disease Research Center.
Ranjan Duara1Florida Alzheimer's Disease Research Center.

Funding

University of Florida - Mt. Sinai Medical Center AD Research CenterP50AG047266 · NIA · UNIVERSITY OF FLORIDA · PI GOLDE, TODD E · 2015 to 2019
$7.3M
Novel Detection of Early Cognitive and Functional Impairment in the ElderlyR01AG047649 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI LOEWENSTEIN, DAVID · 2015 to 2019
$2.7M
NIA NIH HHS P50 AG047266NIA NIH HHS R01 AG047649
6 · The paper itself

Abstract

objectiveThis research aimed to determine whether qualitative analysis of different types of intrusion errors on a verbal cognitive task was useful in detecting subtle cognitive impairment in preclinical stages prior to the progression to dementia.

methodDifferent types of semantic intrusions on the Loewenstein-Acevedo Scales of Semantic Interference and Learning (LASSI-L) were compared across 160 individuals diagnosed as cognitively normal (CN), amnestic Mild Cognitive Impairment (aMCI), and dementia. The sample included Hispanics and non-Hispanic European Americans.

resultsAcross diagnostic groups, the most common type of intrusion error was actual targets presented from a competing word list under conditions eliciting proactive semantic interference (PSI), and retroactive semantic interference (RSI), followed by intrusions that represented one of three overlapping semantic categories but none of the targets from List A or B. Nonsemantic intrusions rarely occurred. These competing list intrusions (CLI) and semantically related intrusions (SRI) differentiated between aMCI and CN participants. Further, these intrusion error were related to brain amyloid load, indicating their importance as potential primary markers of AD-related neurodegeneration. Ethnicity effects were not seen across the types of intrusion errors.

conclusionsTwo types of intrusion errors (CLI and SRI) showed differences between the CN and aMCI group, with the aMCI group evidencing a higher rate of these intrusion errors compared with the CN group. These results support previous literature about the LASSI-L's sensitivity at the earliest stages of abnormal aging. (PsycINFO Database Record (c) 2019 APA, all rights reserved).

Indexed as

AgedAttentionCognitive DysfunctionDementiaFemaleHumansLearningMaleNeuropsychological TestsSemantics

Identifiers

PMID31070384
PMCPMC6731098

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.