Evidence map›Paper›PMID 31075987›Full record

ArticleMolecules (Basel, Switzerland)2019

α-Ionone Protects Against UVB-Induced Photoaging in Human Dermal Fibroblasts.

Tao Tong, Jinju Park, Youna Moon, Wesuk Kang, Taesun Park

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Antiwrinkle and Antimelanogenesis Effects of TyndallizedInternational journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tao TongDepartment of Food and Nutrition, Brain Korea 21 PLUS Project, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea. tongtao1028@163.com.ORCID 0000-0002-9309-2893
Jinju ParkDepartment of Food and Nutrition, Brain Korea 21 PLUS Project, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea. jeanzu@naver.com.ORCID 0000-0002-1748-1264
Youna MoonDepartment of Food and Nutrition, Brain Korea 21 PLUS Project, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea. merryouna@nate.com.
Wesuk KangDepartment of Food and Nutrition, Brain Korea 21 PLUS Project, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea. wesuk42@naver.com.
Taesun ParkDepartment of Food and Nutrition, Brain Korea 21 PLUS Project, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea. tspark@yonsei.ac.kr.ORCID 0000-0002-9752-9407
Yonsei University · KR

Funding

National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) No. 2019R1A2C2003340
6 · The paper itself

Abstract

Ultraviolet (UV) light-induced wrinkle formation is a major dermatological problem and is associated with alteration in collagen. Here, we investigated the potential of α-ionone, a naturally occurring aromatic compound, in regulation of UVB-induced photoaging in human Hs68 dermal fibroblasts and identified the mechanisms involved. We found that in human dermal fibroblasts, α-ionone inhibited UVB-induced loss of collagen. α-Ionone upregulated the molecules participating in the TGF-β-SMAD pathway (TGF-β1, phospho-SMAD2/3,

Indexed as

Ultraviolet RaysCollagenDermisFibroblastsHumansHyaluronic AcidModels, BiologicalNorisoprenoidsSkin AgingUp-Regulationalpha-iononeCollagenHyaluronic AcidNorisoprenoidscollagendermal fibroblastshyaluronic acidphotoagingα-ionone

Identifiers

PMID31075987
PMCPMC6539661
OpenAlexW2943937274

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.