Evidence mapPaperPMID 31079098Full record

SynthesisCardiology

Cardiovascular Risk Factor Control and Lifestyle Factors in Young to Middle-Aged Adults with Newly Diagnosed Obstructive Coronary Artery Disease.

Michael S Garshick, Georgeta D Vaidean, Anish Vani, James A Underberg, Jonathan D Newman, Jeffrey S Berger, Edward A Fisher, Eugenia Gianos

Open access · bronzeAbstract readComparative StudySystematic Review
In one paragraph

Synthesis in Cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
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  4. Article
  5. Article
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  7. Article
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  9. Article
  10. Impact of risk factors related to metabolic syndrome on acute myocardial infarction in younger patients.Hypertension research : official journal of the Japanese Society of Hypertension · 2022
    Review
  11. Article
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  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Michael S GarshickCenter for the Prevention of Cardiovascular Disease, New York University Langone Health, New York City, New York, USA, michael.garshick@nyumc.org.
Georgeta D VaideanCenter for the Prevention of Cardiovascular Disease, New York University Langone Health, New York City, New York, USA.
Anish VaniCenter for the Prevention of Cardiovascular Disease, New York University Langone Health, New York City, New York, USA.
James A UnderbergCenter for the Prevention of Cardiovascular Disease, New York University Langone Health, New York City, New York, USA.
Jonathan D NewmanCenter for the Prevention of Cardiovascular Disease, New York University Langone Health, New York City, New York, USA.
Jeffrey S BergerCenter for the Prevention of Cardiovascular Disease, New York University Langone Health, New York City, New York, USA.
Edward A FisherCenter for the Prevention of Cardiovascular Disease, New York University Langone Health, New York City, New York, USA.
Eugenia GianosDepartment of Cardiology, Lenox Hill Hospital, Northwell Health, New York, New York, USA.
NYU Langone Health · USFairleigh Dickinson University · USLenox Hill Hospital · US

Funding

Training Program in Cardiovascular SciencesT32HL098129 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Glenn I Fishman, Ira J Goldberg · 2009 to 2026
$5.9M
Arsenic Exposure, Diabetes and AtherosclerosisK23HL125991 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI NEWMAN, JONATHAN D · 2016 to 2020
$868k
NHLBI NIH HHS K23 HL125991NHLBI NIH HHS T32 HL098129
6 · The paper itself

Abstract

backgroundWhile progress in the prevention of cardiovascular disease (CVD) has been noted over the past several decades, there are still those who develop CVD earlier in life than others.

objectiveWe investigated traditional and lifestyle CVD risk factors in young to middle-aged patients compared to older ones with obstructive coronary artery disease (CAD).

methodsA retrospective analysis of patients with a new diagnosis of obstructive CAD undergoing coronary intervention was performed. Young to middle-aged patients were defined as those in the youngest quartile (n = 281, mean age 50 ± 6 years, 81% male) compared to the other three older quartiles combined (n = 799, mean age 69 ± 7.5 years, 71% male). Obstructive CAD was determined by angiography.

resultsYoung to middle-aged patients compared to older ones were more likely to be male (p < 0.01), smokers (21 vs. 9%, p < 0.001), and have a higher body mass index (31 ± 6 vs. 29 ± 6 kg/m2, p < 0.001). Younger patients were less likely to eat fruits, vegetables, and fish and had fewer controlled CVD risk factors (2.7 ± 1.2 vs. 3.0 ± 1.0, p < 0.001). Compared to older patients, higher levels of psychological stress (aOR 1.6, 95% CI 1.1-2.4), financial stress (aOR 1.8, 95% CI 1.3-2.5), and low functional capacity (aOR 3.3, 95% CI 2.4-4.5) were noted in the young to middle-aged population as well.

conclusionLifestyle in addition to traditional CVD risk factors should be taken into account when evaluating risk for development of CVD in a younger population.

Indexed as

Life StyleAdultAgedAged, 80 and overBody Mass IndexCoronary AngiographyCoronary Artery DiseaseFemaleHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisNew YorkRetrospective StudiesRisk FactorsAccelerated atherosclerosisCardiovascular risk factorsPreventionPreventive cardiology

Identifiers

PMID31079098
PMCPMC6668015
OpenAlexW2944450392

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.