Evidence map›Paper›PMID 31088299›Full record

ArticleAntioxidants & redox signaling2019

Reactive Oxygen Species-Dependent Calpain Activation Contributes to Airway and Pulmonary Vascular Remodeling in Chronic Obstructive Pulmonary Disease.

Jing Zhu, Laszlo Kovacs, Weihong Han, Guojun Liu, Yuqing Huo, Rudolf Lucas, David Fulton, Peter A Greer, Yunchao Su

Open access · greenAbstract read
In one paragraph

Article in Antioxidants & redox signaling, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. The vascular perspective on acute and chronic lung disease.The Journal of clinical investigation · 2023
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Mechanosensitive channel Piezo1 is required for pulmonary artery smooth muscle cell proliferation.American journal of physiology. Lung cellular and molecular physiology · 2022
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. [Calpain activation promotes dialysis-associated peritoneal fibrosis in rats].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Jing ZhuDepartment of Respiratory and Critical Care Medicine, the People's Hospital of China Three Gorges University, Yichang, China.
Laszlo KovacsDepartment of Pharmacology & Toxicology, Medical College of Georgia, Augusta University, Augusta, Georgia.
Weihong HanDepartment of Pharmacology & Toxicology, Medical College of Georgia, Augusta University, Augusta, Georgia.
Guojun LiuDepartment of Pharmacology & Toxicology, Medical College of Georgia, Augusta University, Augusta, Georgia.
Yuqing HuoVascular Biology Center, Medical College of Georgia, Augusta University, Augusta, Georgia.
Rudolf LucasDepartment of Pharmacology & Toxicology, Medical College of Georgia, Augusta University, Augusta, Georgia.
David FultonDepartment of Pharmacology & Toxicology, Medical College of Georgia, Augusta University, Augusta, Georgia.
Peter A GreerQueen's University Cancer Research Institute, Kingston, Canada.
Yunchao SuDepartment of Pharmacology & Toxicology, Medical College of Georgia, Augusta University, Augusta, Georgia.
Augusta University · USQueen's University · CA

Funding

Circadian origins of vascular disease in obesityR01HL147159 · NHLBI · AUGUSTA UNIVERSITY · PI FULTON, DAVID J, STEPP, DAVID W · 2019 to 2022
$2.7M
ENaC-α mediates lung fluid clearance and capillary barrier function in pneumoniaR01HL138410 · NHLBI · AUGUSTA UNIVERSITY · PI LUCAS, RUDOLF · 2018 to 2021
$2.0M
Airway and Lung Vascular Remodeling in COPDI01BX002035 · VA · CHARLIE NORWOOD VA MEDICAL CENTER · PI SU, YUNCHAO · 2015 to 2018
–
BLRD VA I01 BX002035NHLBI NIH HHS R01 HL138410NHLBI NIH HHS R01 HL147159
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBronchial ArteriesCalpainCell ProliferationCells, CulturedCollagenDisease Models, AnimalHumansHydrogen PeroxideMaleMiceMyocytes, Smooth MusclePulmonary ArteryPulmonary Disease, Chronic ObstructiveRatsReactive Oxygen SpeciesCalpainCollagenHydrogen PeroxideReactive Oxygen SpeciesSmokecalpainCOPDreactive oxygen speciestobacco smoke

Identifiers

PMID31088299
PMCPMC7061305
OpenAlexW2946368559

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.