Evidence mapPaperPMID 31095460Full record

ReviewJournal of applied physiology (Bethesda, Md. : 1985)2019

Edward F. Adolph Distinguished Lecture. Contemporary model of muscle microcirculation: gateway to function and dysfunction.

David C Poole

Abstract readReview
In one paragraph

Review in Journal of applied physiology (Bethesda, Md. : 1985), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
6.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 39 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. KMicrovascular research · 2025
    Article
  5. Pericytes in mouse heart.Frontiers in physiology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Optimal Duration of Cold and Heat Compression for Forearm Muscle Biomechanics in Mixed Martial Arts Athletes: A Comparative Study.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Regulation of capillary hemodynamics by KPhysiological reports · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

David C PooleDepartments of Kinesiology, Anatomy and Physiology, Kansas State University, Manhattan, Kansas.
Kansas State University · US

Funding

VENTILATION BLOOD FLOW IN HEALTH AND DISEASEP01HL017731 · UNIVERSITY OF CALIFORNIA SAN DIEGO · 1985 to 2004
$10.6M
Aging, Chronic Disease and Skeletal Muscle PerfusionR21AG019228 · KANSAS STATE UNIVERSITY · 2001 to 2002
$437k
NHLBI NIH HHS P01 HL017731NHLBI NIH HHS R15 HL108328NIA NIH HHS R21 AG019228
6 · The paper itself

Abstract

This review strikes at the very heart of how the microcirculation functions to facilitate blood-tissue oxygen, substrate, and metabolite fluxes in skeletal muscle. Contemporary evidence, marshalled from animals and humans using the latest techniques, challenges iconic perspectives that have changed little over the past century. Those perspectives include the following: the presence of contractile or collapsible capillaries in muscle, unitary control by precapillary sphincters, capillary recruitment at the onset of contractions, and the notion of capillary-to-mitochondrial diffusion distances as limiting O

Indexed as

AnimalsCapillariesExerciseHeart FailureHumansMicrocirculationMuscle, SkeletalOxygen ConsumptionRegional Blood Flowcapillary hemodynamicsexercise intoleranceheart failureO2 transport pathwayskeletal muscle

Identifiers

PMID31095460
PMCPMC6850982
OpenAlexW2944898996

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.