Evidence map›Paper›PMID 31096521›Full record

SynthesisMedicine2019

Systematic reviews of pharmacological and nonpharmacological treatments for patients with chronic urticaria: An umbrella systematic review.

Yunzhou Shi, Siyuan Zhou, Qianhua Zheng, Ying Huang, Pingsheng Hao, Mingmin Xu, Leixiao Zhang, Xianjun Xiao, Hui Zheng, Ying Li

Open access · goldAbstract readComparative StudySystematic Review
In one paragraph

Synthesis in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yunzhou ShiDepartment of Acupuncture and Moxibustion, Chengdu University of Traditional Chinese Medicine.
Siyuan ZhouDepartment of Acupuncture and Moxibustion, Chengdu University of Traditional Chinese Medicine.
Qianhua ZhengDepartment of Acupuncture and Moxibustion, Chengdu University of Traditional Chinese Medicine.
Ying HuangThe Dermatology Department of the Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, China.
Pingsheng HaoThe Dermatology Department of the Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, China.
Mingmin XuDepartment of Acupuncture and Moxibustion, Chengdu University of Traditional Chinese Medicine.
Leixiao ZhangDepartment of Acupuncture and Moxibustion, Chengdu University of Traditional Chinese Medicine.
Xianjun XiaoDepartment of Acupuncture and Moxibustion, Chengdu University of Traditional Chinese Medicine.
Hui ZhengDepartment of Acupuncture and Moxibustion, Chengdu University of Traditional Chinese Medicine.
Ying LiDepartment of Acupuncture and Moxibustion, Chengdu University of Traditional Chinese Medicine.
Chengdu University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A wide range of pharmacological and nonpharmacological interventions for chronic urticaria (CU) have been evaluated in systematic reviews (SRs). We conducted an umbrella review of SRs of the effectiveness and safety of pharmacological and nonpharmacological interventions for CU, which allow the findings of separate reviews to be compared and contrasted and thereby provide decision makers in healthcare with the evidence they need.We included SRs evaluating pharmacological and nonpharmacological interventions for CU. Comprehensive searches were conducted in 7 bibliographic databases, relevant journals up to July 2018. Two reviewers independently assessed the studies' relevance and quality. The assessment of multiple systematic reviews tool and grading of recommendations assessment, development and evaluation method was used to assess the methodological quality of the SRs and classify the quality of the outcomes.In total, 41 SRs were included. Thirty-seven reviews performed quantitative research syntheses, and 4 reviews performed qualitative research syntheses. The majority of SRs evaluated interventions based on combination therapies, antihistamines, traditional Chinese medicines, autohemotherapy, omalizumab, acupuncture, cyclosporine, and leukotriene receptor antagonist. Positive intervention outcomes were reported in the majority (75.32%) of the reviews. However, the methodological quality and evidence quality of the reviews were generally poor.There is some evidence to support a variety of interventions for CU. However, there was much heterogeneity in evidence quality among SRs. Many of the SRs had methodological weaknesses that make them vulnerable to bias. Moreover, there remained little information on the relative effectiveness of one intervention compared with another. Therefore, further SRs that adherence to strict scientific methods are necessary, and primary studies make comparisons between the different treatment options directly.

Indexed as

Acupuncture TherapyAnti-Allergic AgentsChronic DiseaseCyclosporineDecision MakingFemaleHistamine AntagonistsHumansImmunosuppressive AgentsLeukotriene AntagonistsMaleMedicine, Chinese TraditionalOmalizumabQuality ImprovementTreatment OutcomeUrticariaAnti-Allergic AgentsCyclosporineHistamine AntagonistsImmunosuppressive AgentsLeukotriene AntagonistsOmalizumab

Identifiers

PMID31096521
PMCPMC6531058
OpenAlexW2946404046

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.