Evidence map›Paper›PMID 31096567›Full record

ReviewInternational journal of molecular sciences2019

The Crowded Crosstalk between Cancer Cells and Stromal Microenvironment in Gynecological Malignancies: Biological Pathways and Therapeutic Implication.

Rosalba De Nola, Alessio Menga, Alessandra Castegna, Vera Loizzi, Girolamo Ranieri, Ettore Cicinelli, Gennaro Cormio

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 2 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 2 syntheses or guidelines pooled it, 91 citations in OpenAlex.

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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Rosalba De NolaDepartment of Tissues and Organs Transplantation and Cellular Therapies, D.E.O.T., University of Bari "Aldo Moro", Piazza G. Cesare, 11-Policlinico 70124 Bari, Italy. rosalba.denola@virgilio.it.ORCID 0000-0002-3486-2237
Alessio MengaDepartment of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari "Aldo Moro", Via E. Orabona, 4, 70125 Bari, Italy. mengaalessio@gmail.com.ORCID 0000-0002-2827-5298
Alessandra CastegnaDepartment of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari "Aldo Moro", Via E. Orabona, 4, 70125 Bari, Italy. alessandra.castegna@uniba.it.
Vera LoizziDepartment of Biomedical and Human Oncological Science, 2nd Unit of Obstetrics and Gynecology, University of Bari "Aldo Moro", Piazza G. Cesare, 11-Policlinico 70124 Bari, Italy. vera.loizzi@uniba.it.ORCID 0000-0002-4006-6421
Girolamo RanieriInterventional Oncology Unit with Integrate Section of Translational Medical Oncology, IRCCS, Istituto Tumori Giovanni Paolo II, 70124 Bari, Italy. giroran@tiscali.it.ORCID 0000-0001-8779-1957
Ettore CicinelliDepartment of Biomedical and Human Oncological Science, 2nd Unit of Obstetrics and Gynecology, University of Bari "Aldo Moro", Piazza G. Cesare, 11-Policlinico 70124 Bari, Italy. ettore.cicinelli@uniba.it.
Gennaro CormioDepartment of Biomedical and Human Oncological Science, 2nd Unit of Obstetrics and Gynecology, University of Bari "Aldo Moro", Piazza G. Cesare, 11-Policlinico 70124 Bari, Italy. gennaro.cormio@uniba.it.
University of Bari Aldo Moro · ITIstituto Tumori Bari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The tumor microenvironment plays a pillar role in the progression and the distance dissemination of cancer cells in the main malignancies affecting women-epithelial ovarian cancer, endometrial cancer and cervical cancer. Their

Indexed as

ActinsChemokinesCytokinesEndometrial NeoplasmsEstrogen Receptor alphaEstrogensFemaleFibroblastsHumansImmune ToleranceLymphocytesLymphocytes, Tumor-InfiltratingMacrophagesMesodermOncogene ProteinsOvarian NeoplasmsActinsChemokinesCytokinesEstrogen Receptor alphaEstrogensOncogene ProteinsReceptor, Platelet-Derived Growth Factor betacervical cancerendometrial cancerestrogensfibroblastsHuman Papilloma Viruslymphocytesovarian cancerpericytestumor-associated macrophages

Identifiers

PMID31096567
PMCPMC6567055
OpenAlexW2945890405

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.