Evidence map›Paper›PMID 31097582›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Ammonia generation by tryptophan synthase drives a key genetic difference between genital and ocular

Shardulendra P Sherchand, Ashok Aiyar

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Metabolism and physiology of pathogenic bacterial obligate intracellular parasites.Frontiers in cellular and infection microbiology · 2024
    Review
  4. Association ofFrontiers in cellular and infection microbiology · 2023
    Article
  5. First-Void Urine Microbiome in Women withInternational journal of molecular sciences · 2022
    Article
  6. The role of tryptophan inFrontiers in cellular and infection microbiology · 2022
    Review
  7. Vaginal and Anal Microbiome duringPathogens (Basel, Switzerland) · 2021
    Article
  8. Article
  9. Article
  10. Differences in the Genital Microbiota in Women Who Naturally ClearFrontiers in cellular and infection microbiology · 2021
    Article
  11. Article
  12. Article
  13. HowProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
4 · The record

Corrections and comments

  • Commented on by
    How2019
5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Shardulendra P SherchandDepartment of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center New Orleans, New Orleans, LA 70112.
Ashok AiyarDepartment of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center New Orleans, New Orleans, LA 70112 aaiyar@lsuhsc.edu.
Louisiana State University Health Sciences Center New Orleans · US

Funding

Consequences of vaginal microbiota on IFNγ-mediated clearance of Chlamydia trachomatisR01AI118860 · NIAID · LSU HEALTH SCIENCES CENTER · PI AIYAR, ASHOK A, QUAYLE, ALISON J. · 2017 to 2020
$2.4M
NIAID NIH HHS R01 AI118860
6 · The paper itself

Abstract

A striking difference between genital and ocular clinical isolates of

Indexed as

AmmoniaChlamydia InfectionsChlamydia trachomatisEyeGenitaliaHumansTryptophanTryptophan SynthaseAmmoniaTryptophanTryptophan SynthaseChlamydia trachomatisgenital and ocular serovarsserine deaminationtrp operon de-repressiontryptophan synthase β-elimination

Identifiers

PMID31097582
PMCPMC6589672
OpenAlexW2944829287

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.