Evidence map›Paper›PMID 31100985›Full record

ReviewCancers2019

Pretreatment Cancer-Related Cognitive Impairment-Mechanisms and Outlook.

Brennan Olson, Daniel L. Marks

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 4 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 4 syntheses or guidelines pooled it, 107 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Risk factors for cancer-related cognitive impairment among individuals with lung cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Observational
  8. Cancer treatment-related cognitive impairment.Neuro-oncology advances · 2026
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Observational
  19. Incidence and predictors of immune checkpoint inhibitor treatment-related cognitive impairment in a racial and ethnic diverse population.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Brennan OlsonMedical Scientist Training Program, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA. olsobr@ohsu.edu.ORCID 0000-0003-2803-5363
Daniel L. MarksPapé Family Pediatric Research Institute, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA. marksd@ohsu.edu.ORCID 0000-0003-2675-7047
Oregon Health & Science University · US

Funding

Exosomes as Endocrine Signaling Molecules in Cancer CachexiaR01CA217989 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI MARKS, DANIEL L. · 2018 to 2022
$2.2M
PQ6: Lipocalin-2 as a therapeutic target for prevention of cancer cachexiaR01CA257452 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI ZIMMERS, TERESA A · 2021 to 2025
$1.9M
The Role of Lipocalin 2 in Cancer CachexiaF30CA254033 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI OLSON, BRENNAN GLENN · 2020 to 2021
$97k
NCI NIH HHS F30 CA254033NCI NIH HHS R01 CA217989NCI NIH HHS R01 CA257452Office of Extramural Research, National Institutes of Health CA217989
6 · The paper itself

Abstract

Cognitive changes are common in patients with active cancer and during its remission. This has largely been blamed on therapy-related toxicities and diagnosis-related stress, with little attention paid to the biological impact of cancer itself. A plethora of clinical studies demonstrates that cancer patients experience cognitive impairment during and after treatment. However, recent studies show that a significant portion of patients with non-central nervous system (CNS) tumors experience cognitive decline

Indexed as

blood-brain barriercachexiaCancercognitive declinecytokinesextracellular vesiclesneuroinflammation

Identifiers

PMID31100985
PMCPMC6562730
OpenAlexW2946403381

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.