Evidence map›Paper›PMID 31109974›Full record

ArticleAntimicrobial agents and chemotherapy2019

Amino Acid Biosynthetic Pathways Are Required for

Rebecca J Silver, Michelle K Paczosa, Anne L McCabe, Joan-Miquel Balada-Llasat, James D Baleja, Joan Mecsas

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Sedative choice altersInfection and immunity · 2026
    Article
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  3. Gene dependence during mammalianMicrobial genomics · 2025
    Article
  4. Arginine utilization inInfection and immunity · 2025
    Article
  5. Review
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  7. Article
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  9. Article
  10. Metagenome Analysis of the Bacterial Characteristics in InvasiveFrontiers in cellular and infection microbiology · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rebecca J Silver *Graduate Program in Immunology, MERGE-ID Track, Sackler School of Biomedical Sciences, Tufts University School of Medicine, Boston, Massachusetts, USA.
Michelle K Paczosa *Graduate Program in Immunology, MERGE-ID Track, Sackler School of Biomedical Sciences, Tufts University School of Medicine, Boston, Massachusetts, USA.
Anne L McCabeDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.
Joan-Miquel Balada-LlasatDepartment of Pathology, The Ohio State Wexner Medical Center, Columbus, Ohio, USA.
James D BalejaDepartment of Developmental, Molecular, and Chemical Biology, Tufts University School of Medicine, Boston, Massachusetts, USA.
Joan MecsasGraduate Program in Immunology, MERGE-ID Track, Sackler School of Biomedical Sciences, Tufts University School of Medicine, Boston, Massachusetts, USA joan.mecsas@tufts.edu.ORCID 0000-0001-9455-6672
Tufts University · USThe Ohio State University Wexner Medical Center · US

Funding

MOLECULAR ANALYSIS OF MICROBIAL PATHOGENST32AI007422 · NIAID · TUFTS UNIVERSITY BOSTON · PI Ralph R. Isberg · 1992 to 2026
$5.7M
IMMUNOLOGIC ASPECTS OF DISEASET32AI007077 · NIAID · TUFTS UNIVERSITY BOSTON · PI WORTIS, HENRY H. · 1985 to 2017
$3.5M
Initiation and regulation of antibacterial innate immunityR01AI113166 · NIAID · TUFTS UNIVERSITY BOSTON · PI MECSAS, JOAN C · 2014 to 2018
$2.4M
Bifunctional Control of Yop Translocation by YopKR01AI107055 · NIAID · TUFTS UNIVERSITY BOSTON · PI MARKETON, MELANIE · 2013 to 2017
$1.9M
UPGRADE AND CRYOGENIC PROBE FOR A 600 MHZ NMR SYSTEM FOR BIOMEDICAL RESEARCHS10OD020073 · OD · TUFTS UNIVERSITY BOSTON · PI BACHOVCHIN, WILLIAM W · 2016 to 2016
$600k
NIAID NIH HHS R01 AI107055NIAID NIH HHS R01 AI113166NIAID NIH HHS T32 AI007077NIAID NIH HHS T32 AI007422NIH HHS S10 OD020073
6 · The paper itself

Abstract

The emergence of multidrug-resistant

Indexed as

Amino AcidsAnimalsAnti-Bacterial AgentsBacterial ProteinsBiosynthetic PathwaysDrug Resistance, Multiple, BacterialFemaleGlycineGlyphosateImmunocompromised HostKlebsiella pneumoniaeLungMiceAmino AcidsAnti-Bacterial AgentsBacterial ProteinsGlycineGlyphosateamino acid biosynthesisaroAglyphosateKlebsiella pneumoniaemultidrug resistantneutropenic

Identifiers

PMID31109974
PMCPMC6658747
OpenAlexW2945265881

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.