Evidence map›Paper›PMID 31114196›Full record

ReviewInternational journal of nanomedicine2019

Nanomedicine-based formulations containing ω-3 polyunsaturated fatty acids: potential application in cardiovascular and neoplastic diseases.

Simona Serini, Roberta Cassano, Sonia Trombino, Gabriella Calviello

Open access · goldAbstract readReview
In one paragraph

Review in International journal of nanomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
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  5. Article
  6. Article
  7. Article
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  10. Article
  11. Iron as a therapeutic target in chronic liver disease.World journal of gastroenterology · 2023
    Review
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  14. Article
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  19. Potential of Nanonutraceuticals in Increasing Immunity.Nanomaterials (Basel, Switzerland) · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Simona SeriniInstitute of General Pathology, Università Cattolica del Sacro Cuore, 00168 Roma, Italy, gabriella.calviello@unicatt.it.
Roberta CassanoDepartment of Pharmacy, Health and Nutritional Sciences, Università della Calabria, 87036 Cosenza, Italy, sonia.trombino@unical.it.
Sonia TrombinoDepartment of Pharmacy, Health and Nutritional Sciences, Università della Calabria, 87036 Cosenza, Italy, sonia.trombino@unical.it.
Gabriella CalvielloInstitute of General Pathology, Università Cattolica del Sacro Cuore, 00168 Roma, Italy, gabriella.calviello@unicatt.it.
Università Cattolica del Sacro Cuore · ITUniversity of Calabria · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Omega-3 polyunsaturated fatty acids (ω-3 PUFAs) are dietary factors involved in the prevention of cardiovascular, inflammatory, and neoplastic diseases. A multidisciplinary approach - based on recent findings in nutritional science, lipid biochemistry, biotechnology, and biology of inflammation and cancer - has been recently employed to develop ω-3 PUFA-containing nanoformulations with an aim to protect these fatty acids from degradation, increase their bioavailability and delivery to target tissues, and, thus, enhance their bioactivity. In some cases, these nanoformulations were designed to administer ω-3 PUFAs in combination with other nutraceuticals or conventional/innovative drugs. The aim of this strategy was to increase the activities of the compounds contained in the nanoformulation and to reduce the adverse effects often induced by drugs. We herein analyze the results of papers evaluating the potential use of ω-3 PUFA-containing nanomaterials in fighting cardiovascular diseases and cancer. Future directions in this field of research are also provided.

Indexed as

Drug CompoundingNanomedicineCardiovascular DiseasesFatty Acids, Omega-3HumansNeoplasmsTreatment OutcomeFatty Acids, Omega-3cancercardiovascular diseasesinnovative biotechnologiesnanoparticlesω-3 PUFAs

Identifiers

PMID31114196
PMCPMC6488162
OpenAlexW2939385124

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.