Evidence map›Paper›PMID 31114965›Full record

ArticleInternational archives of occupational and environmental health2019

A study of atherothrombotic biomarkers in welders.

Dag G Ellingsen, Maxim Chashchin, Ingebjørg Seljeflot, Balazs Berlinger, Valery Chashchin, Leo Stockfelt, Yngvar Thomassen

Abstract read
PubMed Publisher
In one paragraph

Article in International archives of occupational and environmental health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dag G EllingsenNational Institute of Occupational Health, P.O. Box 5330 Dep, 0304, Oslo, Norway. dag.ellingsen@stami.no.ORCID 0000-0002-7607-6701
Maxim ChashchinNorthwest Public Health Research Centre, Saint Petersburg, Russia.
Ingebjørg SeljeflotDepartment of Cardiology, Center for Clinical Heart Research, Oslo University Hospital, Ullevål, Norway.
Balazs BerlingerNational Institute of Occupational Health, P.O. Box 5330 Dep, 0304, Oslo, Norway.
Valery ChashchinNorthwest Public Health Research Centre, Saint Petersburg, Russia.
Leo StockfeltDepartment of Occupational and Environmental Medicine, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden.
Yngvar ThomassenNational Institute of Occupational Health, P.O. Box 5330 Dep, 0304, Oslo, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionStudies have shown that welders have increased cardiovascular mortality. This may be due to airborne particulate matter (PM) exposure. Elevated levels of PM in polluted urban air have been associated with increased cardiovascular mortality and morbidity. This study seeks to explore potential mechanisms for the increased cardiovascular mortality in welders.

methodsSeventy welders were compared to 74 referents. Exposure to PM was assessed by personal full-shift sampling of work room air the last 2 days before collection of blood samples. Selected biomarkers of pro-coagulant activity, endothelial/platelet activation and systemic inflammation were determined in the samples.

resultsThe welders had been occupationally exposed to PM for 15 years on average. The geometric mean current exposure to PM was 8.1 mg/m DISCUSSION: The study shows that welders highly exposed to welding PM were in a pro-thrombotic state with increased thrombin generation and consequently higher D-dimer concentrations. The welders had also increased endothelial/platelet activation as compared to the referents. These alterations are compatible with increased cardiovascular mortality as previously reported among welders.

Indexed as

WeldingAdultAgedAir Pollutants, OccupationalBiomarkersCross-Sectional StudiesFibrin Fibrinogen Degradation ProductsHumansMaleMiddle AgedOccupational ExposureParticle SizeParticulate MatterPlatelet ActivationRussiaThrombinAir Pollutants, OccupationalBiomarkersFibrin Fibrinogen Degradation Productsfibrin fragment DParticulate MatterThrombinBiomarkersCardiovascular diseaseEndothelial activationThrombosisWelders

Identifiers

PMID31114965

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.