Evidence map›Paper›PMID 31116668›Full record

ArticleMolecular biology of the cell2019

Fission yeast TRP channel Pkd2p localizes to the cleavage furrow and regulates cell separation during cytokinesis.

Zachary Morris, Debatrayee Sinha, Abhishek Poddar, Brittni Morris, Qian Chen

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Regulation of Yeast Cytokinesis by Calcium.Journal of fungi (Basel, Switzerland) · 2025
    Review
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  5. The role ofbioRxiv : the preprint server for biology · 2024
    Article
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  7. The Role ofIntegrative organismal biology (Oxford, England) · 2024
    Article
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  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zachary MorrisDepartment of Biological Sciences, University of Toledo, Toledo, OH 43606.
Debatrayee SinhaDepartment of Biological Sciences, University of Toledo, Toledo, OH 43606.
Abhishek PoddarDepartment of Biological Sciences, University of Toledo, Toledo, OH 43606.
Brittni MorrisDepartment of Biological Sciences, University of Toledo, Toledo, OH 43606.
Qian ChenDepartment of Biological Sciences, University of Toledo, Toledo, OH 43606.
University of California, San Francisco · USUniversity of Toledo · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Force plays a central role in separating daughter cells during cytokinesis, the last stage of cell division. However, the mechanism of force sensing during cytokinesis remains unknown. Here we discovered that Pkd2p, a putative force-sensing transient receptor potential channel, localizes to the cleavage furrow during cytokinesis of the fission yeast,

Indexed as

CytokinesisCell ProliferationEpistasis, GeneticGenes, EssentialMutationProtein TransportSchizosaccharomycesSchizosaccharomyces pombe ProteinsTransient Receptor Potential ChannelsPkd2p protein, S pombeSchizosaccharomyces pombe ProteinsTransient Receptor Potential Channels

Identifiers

PMID31116668
PMCPMC6727746
OpenAlexW2946006621

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.