Evidence map›Paper›PMID 31117270›Full record

ArticleAnimals : an open access journal from MDPI2019

Genome-Wide Association Study of H/L Traits in Chicken.

Bo Zhu, Qinghe Li, Ranran Liu, Maiqing Zheng, Jie Wen, Guiping Zhao

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Bo ZhuInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China. boyzhubo@126.com.
Qinghe LiInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China. liqinghe@caas.cn.
Ranran LiuInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China. liuranran@caas.cn.
Maiqing ZhengInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China. zhengmaiqing@caas.cn.
Jie WenInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China. wenjie@caas.cn.
Guiping ZhaoInstitute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China. zhaoguiping@caas.cn.
Chinese Academy of Agricultural Sciences · CNState Key Laboratory of Animal Nutrition

Funding

National Hightech R&D Program 2015BAD03B03
6 · The paper itself

Abstract

Presently, the heterophil-to-lymphocyte (H/L) ratio is being studied extensively as a disease resistance trait. Through intricate mechanisms to identify and destroy pathogenic microorganisms, heterophils play a pivotal role in the immune defense systems of avian species. To reveal the genetic basis and molecular mechanisms affecting the H/L ratio, phenotypic and H/L data from 1650 white feather chicken broilers were used in performing a genome-wide association study. A self-developed, chicken-specific 55K chip was used for heterophils, lymphocytes, and H/L classification, according to individual genomic DNA profiles. We identified five significant single nucleotide polymorphisms (SNPs) when the genome-wide significance threshold was set to 5% (

Indexed as

chickenGWASheterophilslymphocyteSNP

Identifiers

PMID31117270
PMCPMC6562784
OpenAlexW2946316275

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.