Evidence map›Paper›PMID 31119982›Full record

ArticleStem cells and development2019

Acid-Sensitive Ion Channels Are Expressed in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Xiao-Hua Zhang, Tomo Šarić, Narges Zare Mehrjardi, Sarkawt Hamad, Martin Morad

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stem cells and development, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. CaCell calcium · 2020
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Xiao-Hua Zhang1Cardiac Signaling Center of University of South Carolina, Medical University of South Carolina, Clemson University, Charleston, South Carolina.
Tomo Šarić2Medical Faculty, Center for Physiology and Pathophysiology, Institute for Neurophysiology, University of Cologne, Cologne, Germany.
Narges Zare Mehrjardi2Medical Faculty, Center for Physiology and Pathophysiology, Institute for Neurophysiology, University of Cologne, Cologne, Germany.
Sarkawt Hamad2Medical Faculty, Center for Physiology and Pathophysiology, Institute for Neurophysiology, University of Cologne, Cologne, Germany.
Martin Morad1Cardiac Signaling Center of University of South Carolina, Medical University of South Carolina, Clemson University, Charleston, South Carolina.
University of Cologne · DEMedical University of South Carolina · US

Funding

ELECTROPHYSIOLOGY OF NEONATAL AND ADULT HEARTSR01HL016152 · NHLBI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI MORAD, MARTIN · 1985 to 2014
$4.5M
NHLBI NIH HHS R01 HL016152
6 · The paper itself

Abstract

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are potential sources for cardiac regeneration and drug development. hiPSC-CMs express all the cardiac ion channels and the unique cardiac Ca

Indexed as

Cell DifferentiationGene Expression RegulationAcid Sensing Ion ChannelsCell Line, TumorDermisFibroblastsHumansInduced Pluripotent Stem CellsMyocytes, CardiacAcid Sensing Ion Channelsacid sensitive ion channels (ASIC)amiloridecardiomyocyteselectrophysiologyhuman induced pluripotent stem cells (hiPSCs)

Identifiers

PMID31119982
PMCPMC6648204
OpenAlexW2945573030

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.