Evidence map›Paper›PMID 31130987›Full record

ArticleFrontiers in genetics2019

Defective Expression of Mitochondrial, Vacuolar H

Xiaoyang Gao, Jing Xu, Hao Chen, Dingwu Xue, Wenju Pan, Chuanman Zhou, Yongchao C Ma, Long Ma

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Mitochondrial Dysfunction in Spinal Muscular Atrophy.International journal of molecular sciences · 2022
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Xiaoyang GaoCenter for Medical Genetics, School of Life Sciences, Central South University, Changsha, China.
Jing XuCenter for Medical Genetics, School of Life Sciences, Central South University, Changsha, China.
Hao ChenCenter for Medical Genetics, School of Life Sciences, Central South University, Changsha, China.
Dingwu XueCenter for Medical Genetics, School of Life Sciences, Central South University, Changsha, China.
Wenju PanCenter for Medical Genetics, School of Life Sciences, Central South University, Changsha, China.
Chuanman ZhouCenter for Medical Genetics, School of Life Sciences, Central South University, Changsha, China.
Yongchao C MaDepartment of Pediatrics, Northwestern University Feinberg School of Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States.
Long MaCenter for Medical Genetics, School of Life Sciences, Central South University, Changsha, China.
Central South University · CNNorthwestern University · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Regulation of Mitochondrial Function and Motor Neuron Degeneration in SMAR01NS094564 · NINDS · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI MA, YONGCHAO CHARLES · 2015 to 2019
$1.6M
Rescuing Motor Neuron Mitochondrial Defects in SMA by Mitigating Cdk5 ActivationR21NS106307 · NINDS · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI MA, YONGCHAO CHARLES · 2018 to 2019
$421k
NIH HHS P40 OD010440NINDS NIH HHS R01 NS094564NINDS NIH HHS R21 NS106307
6 · The paper itself

Abstract

Spinal muscular atrophy (SMA) is a severe motor neuron degenerative disease caused by loss-of-function mutations in the survival motor neuron gene

Indexed as

C. eleganshistonemitochondriaSMNvacuolar H+-ATPase

Identifiers

PMID31130987
PMCPMC6509145
OpenAlexW2943575450

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.