SynthesisEuropean journal of preventive cardiology2019
Hypertensive disorders of pregnancy and cardiometabolic outcomes in childhood: A systematic review.
Synthesis in European journal of preventive cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Association of hypertensive disorders of pregnancy with offspring cardiometabolic indicators: a systematic review and meta-analysis.Frontiers in endocrinology · 2025Pooled it
- Pooled it
- Association between hypertensive disorders during pregnancy and elevated blood pressure in offspring: A systematic review and meta-analysis.Journal of clinical hypertension (Greenwich, Conn.) · 2022Pooled it
- Cardiovascular Disease in Singleton Offspring Born of Pregnancies Complicated by Placental Abruption: A Population-Based Retrospective Cohort Study.Journal of the American Heart Association · 2026Article
- The effect of Akkermansia in patients with pregnancy induced hypertension.BMC microbiology · 2025Article
- The Role of the Intrauterine Environment in Shaping Childhood and Adolescence Metabolic Outcomes.Metabolites · 2025Review
- Article
- Article
- The Association between Gut Microbiome and Pregnancy-Induced Hypertension: A Nested Case-Control Study.Nutrients · 2022Article
- Association of Maternal Preeclampsia With Offspring Risks of Ischemic Heart Disease and Stroke in Nordic Countries.JAMA network open · 2022Article
- Maternal diet, nutritional status and infant birth weight in Malaysia: a scoping review.BMC pregnancy and childbirth · 2022Article
- Childhood Blood Pressure, Carotid Intima Media Thickness, and Distensibility After In Utero Exposure to Gestational Hypertensive Disorders.Journal of the American Heart Association · 2022Article
- Impact of offspring endothelial function fromFrontiers in surgery · 2022Review
- Investigating a Potential Causal Relationship Between Maternal Blood Pressure During Pregnancy and Future Offspring Cardiometabolic Health.Hypertension (Dallas, Tex. : 1979) · 2022Article
- Association of Placental Pathology With Childhood Blood Pressure Among Children Born Preterm.American journal of hypertension · 2021Article
- Information needs and experiences from pregnancies complicated by hypertensive disorders: a qualitative analysis of narrative responses.BMC pregnancy and childbirth · 2021Observational
- Early Determinants of Childhood Blood Pressure at the Age of 6 Years: The GECKO Drenthe and ABCD Study Birth Cohorts.Journal of the American Heart Association · 2020Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHypertensive disorders of pregnancy (HDPs) are among the leading causes of maternal and perinatal morbidity and mortality worldwide and have been suggested to increase long-term cardiovascular disease risk in the offspring.
objectiveThe objective of this study was to investigate whether HDPs are associated with cardiometabolic markers in childhood. SEARCH STRATEGY: PubMed, The Cochrane Library and reference lists of included studies up to January 2019. SELECTION CRITERIA: Studies comparing cardiometabolic markers in 2-18-year-old children of mothers with HDP in utero, to children of mothers without HDP. DATA COLLECTION AND ANALYSIS: Sixteen studies reported in 25 publications were included in this systematic review, of which three were considered as having high risk of bias. Thus 13 studies were included in the evidence synthesis: respectively two and eight reported pregnancy induced hypertension and preeclampsia, and three studies reported on both HDPs. MAIN
resultsMost studies (
conclusionsMost studies showed that exposure to pregnancy induced hypertension is associated with a higher offspring blood pressure. There is no convincing evidence for an association between exposure to preeclampsia and blood pressure in childhood. Based on current evidence, exposure to HDP is not associated with blood levels of cholesterol, triglycerides and glucose in childhood.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.