Evidence mapPaperPMID 31132952Full record

ArticleHypertension (Dallas, Tex. : 1979)2019

Pulse Wave Velocities Derived From Cuff Ambulatory Pulse Wave Analysis.

Joseph E Schwartz, Peter U Feig, Joseph L Izzo

Open access · bronzeAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 66 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Joseph E SchwartzFrom the Department of Psychiatry and Behavioral Health, Renaissance School of Medicine, Stony Brook School of Medicine, NY (J.E.S.).
Peter U FeigDepartment of Medicine, Weill Cornell Medical College, New York, NY (P.U.F.).
Joseph L IzzoDepartment of Medicine, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, NY (J.L.I.).
Cornell University · USStony Brook School · US

Funding

WORKSITE BLOOD PRESSURE STUDYP01HL047540 · WEILL MEDICAL COLLEGE OF CORNELL UNIV · 1993 to 2005
$10.8M
NHLBI NIH HHS P01 HL047540NHLBI NIH HHS R01 HL114082
6 · The paper itself

Abstract

Pulse wave velocity (PWV), a measure of arterial stiffness, is an independent risk factor for cardiovascular morbidity and mortality. We investigated the relationship of ambulatory brachial cuff-based oscillometric PWV (oPWV) to 2 known correlates: age and brachial systolic blood pressure (SBP). In 234 participants in the Masked Hypertension Study, we analyzed 7284 validated hourly ambulatory SBP and oPWV readings using the Mobil-O-Graph monitor, which uses a proprietary pulse wave analysis algorithm to determine oPWV. Carotid-femoral PWV (cfPWV) was also measured. Mixed linear models were developed to estimate oPWV from age and ambulatory SBP. Participants were 34% male, with mean (SD) age 52.8 (9.9) years, SBP 123.8 (18.4) mm Hg, and oPWV 7.6 (1.3) m/s and cfPWV of 7.7 (1.7) m/s. The relationship of oPWV to age and SBP is given below: [Formula: see text] Age uniquely accounted for an estimated 75% of the total variation of oPWV, whereas SBP uniquely accounted for 20%; these findings were confirmed in an external validation dataset. Together, age and SBP accounted for 99.1% of the total variance of oPWV but (only) 40.2% of the variance of cfPWV. The correlation between oPWV and cfPWV was 0.58 but was only 0.11 after controlling for age and SBP. We conclude that the Mobil-O-Graph's oPWV is nearly completely explained by age and SBP and its relationship to cfPWV is because of their shared associations with age and SBP. Other hemodynamic variables derived from oscillometric pulse wave analysis may be useful and deserve additional scrutiny.

Indexed as

Blood Pressure Monitoring, AmbulatoryAdultAgedAge FactorsBlood Pressure DeterminationCardiovascular DiseasesCohort StudiesDatabases, FactualFemaleFollow-Up StudiesHemodynamicsHumansMaleMasked HypertensionMiddle AgedPulse Wave Analysisblood pressurehemodynamicspulse wave analysis

Identifiers

PMID31132952
PMCPMC6679929
OpenAlexW2949771544

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.