Evidence map›Paper›PMID 31149031›Full record

ArticleDiabetology & metabolic syndrome2019

Higher adiponectin concentrations are associated with reduced metabolic syndrome risk independently of weight status in Brazilian adolescents.

Karen Sparrenberger, Mariana Sbaraini, Felipe Vogt Cureau, Gabriela Heiden Teló, Luciana Bahia, Beatriz D Schaan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diabetology & metabolic syndrome, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Food Consumption and Metabolic Risks in Young University Students.International journal of environmental research and public health · 2021
    Article
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Karen Sparrenberger1Postgraduate Program in Endocrinology, Universidade Federal do Rio Grande do Sul-Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos 2350, Prédio 21, 6º andar, Porto Alegre, RS 90035-003 Brazil.
Mariana Sbaraini2Postgraduate Program in Cardiology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Felipe Vogt Cureau1Postgraduate Program in Endocrinology, Universidade Federal do Rio Grande do Sul-Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos 2350, Prédio 21, 6º andar, Porto Alegre, RS 90035-003 Brazil.
Gabriela Heiden Teló1Postgraduate Program in Endocrinology, Universidade Federal do Rio Grande do Sul-Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos 2350, Prédio 21, 6º andar, Porto Alegre, RS 90035-003 Brazil.
Luciana Bahia2Postgraduate Program in Cardiology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Beatriz D Schaan1Postgraduate Program in Endocrinology, Universidade Federal do Rio Grande do Sul-Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos 2350, Prédio 21, 6º andar, Porto Alegre, RS 90035-003 Brazil.
Universidade Federal do Rio Grande do Sul · BRHospital de Clínicas de Porto Alegre · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the association between adiponectin concentrations and metabolic syndrome (MetS) risk and to investigate if this association is independent of weight status in adolescents.

methodsAdiponectin concentrations and MetS risk were assessed in 4546 Brazilian adolescents (12-17 years old) enrolled in The Study of Cardiovascular Risks in Adolescents ("ERICA"), a cross-sectional multicenter study in Brazil. For analyses, adiponectin was categorized in sex and age-specific quartiles and MetS risk was expressed as a continuous score, calculated as the average of the standardized values (z-score) of the five MetS components. Multiple linear regression models were used to investigate the association between the quartiles of adiponectin and MetS risk.

resultsAdiponectin was inversely associated with waist circumference and log-transformed triglycerides, and positively associated with HDL-c. We also observed an inverse association between adiponectin concentrations and MetS risk. After adjustment for sociodemographic variables, physical activity, skipping breakfast and body mass index (BMI), higher quartiles of adiponectin remained inversely associated with waist circumference and MetS risk. A direct association between adiponectin and HDL-c was also observed. In further analysis, the sample was stratified by weight status and an inverse association between quartiles of adiponectin and MetS risk was observed in both normal weight and overweight/obese adolescents.

conclusionHigher adiponectin concentrations were independently and inverse associated with MetS risk in Brazilian adolescents, even after adjusting for BMI. These results were similar in normal weight and overweight/obese adolescents, suggesting that adiponectin may play a role in early development of MetS.

Indexed as

AdiponectinAdolescentsMetabolic syndromeObesityPediatric

Identifiers

PMID31149031
PMCPMC6534928
OpenAlexW2947150072

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.