Evidence map›Paper›PMID 31156427›Full record

ReviewFrontiers in pharmacology2019

Asteraceae Plants as Sources of Compounds Against Leishmaniasis and Chagas Disease.

Roberval Nascimento Moraes Neto, Ruth Flávia Barros Setúbal, Taciana Mirely Maciel Higino, Maria Carolina Accioly Brelaz-de-Castro, Luís Cláudio Nascimento da Silva, Amanda Silva Dos Santos Aliança

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. ACS omega · 2026
    Article
  3. Article
  4. The GenusPlants (Basel, Switzerland) · 2025
    Review
  5. Frontiers in pharmacology · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Human Lung Cancer (A549) Cell Line Cytotoxicity and Anti-Pharmaceuticals (Basel, Switzerland) · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Roberval Nascimento Moraes NetoPrograma de Pós-Graduação da Universidade Ceuma, São Luís, Brazil.
Ruth Flávia Barros SetúbalPrograma de Pós-Graduação da Universidade Ceuma, São Luís, Brazil.
Taciana Mirely Maciel HiginoDepartamento de Investigação Científica, Fundação Altino Ventura, Recife, Brazil.
Maria Carolina Accioly Brelaz-de-CastroDepartamento de Enfermagem, Universidade Federal de Pernambuco, Vitória de Santo Antão, Brazil.
Luís Cláudio Nascimento da SilvaPrograma de Pós-Graduação da Universidade Ceuma, São Luís, Brazil.
Amanda Silva Dos Santos AliançaPrograma de Pós-Graduação da Universidade Ceuma, São Luís, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leishmaniasis and Chagas disease cause great impact on social and economic aspects of people living in developing countries. The treatments for these diseases are based on the same regimen for over 40 years, thus, there is an urgent need for the development of new drugs. In this scenario, Asteraceae plants (a family widely used in folk medicine worldwide) are emerging as an interesting source for new trypanocidal and leishmanicidal compounds. Herein, we provide a non-exhaustive review about the activity of plant-derived products from Asteraceae with inhibitory action toward

Indexed as

asteraceae plantsLeishmania spp.leishmanicidal activitytrypanocidal activityTrypanosoma cruzitrypanosomatids

Identifiers

PMID31156427
PMCPMC6530400

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.