Evidence mapPaperPMID 31157538Full record

ArticleBiomarkers in medicine2019

Ethnogeographic prevalence and implications of the 677C>T and 1298A>C

James S Graydon, Karla Claudio, Seth Baker, Mohan Kocherla, Mark Ferreira, Abiel Roche-Lima, Jovaniel Rodríguez-Maldonado, Jorge Duconge, Gualberto Ruaño

Open access · greenAbstract read
In one paragraph

Article in Biomarkers in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
  2. Review
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  5. Retinal vascular dysfunction in the MthfrAlzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  6. Review
  7. Children (Basel, Switzerland) · 2025
    Review
  8. Article
  9. Article
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  13. Review
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  15. Review
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  17. Article
  18. Association ofNeurology · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

James S GraydonLaboratory of Personalized Health, Genomas, Inc., Hartford, CT 06102, USA.
Karla ClaudioPharmaceutical Sciences department, University of Puerto Rico School of Pharmacy, San Juan, PR 00936, USA.
Seth BakerClinical Laboratory Partners, Hartford Healthcare, Hartford, CT 06102, USA.
Mohan KocherlaLaboratory of Personalized Health, Genomas, Inc., Hartford, CT 06102, USA.
Mark FerreiraLaboratory of Personalized Health, Genomas, Inc., Hartford, CT 06102, USA.
Abiel Roche-LimaCenter for Collaborative Research in Health Disparities, University of Puerto Rico School of Medicine, San Juan, PR 00936, USA.
Jovaniel Rodríguez-MaldonadoCenter for Collaborative Research in Health Disparities, University of Puerto Rico School of Medicine, San Juan, PR 00936, USA.
Jorge DucongePharmaceutical Sciences department, University of Puerto Rico School of Pharmacy, San Juan, PR 00936, USA.
Gualberto RuañoLaboratory of Personalized Health, Genomas, Inc., Hartford, CT 06102, USA.
University of Puerto Rico System · PRHartford Financial Services (United States)Genomas (United States) · USGTx (United States) · US

Funding

The Microbiome as a risk factor for hr-HPV persistence and Cervical CancerU54MD007600 · UNIVERSITY OF PUERTO RICO MED SCIENCES · 2025 to 2025
$3.5M
NHLBI NIH HHS SC1 HL123911NIMHD NIH HHS U54 MD007600
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

GeographyPolymorphism, Single NucleotideAdolescentAdultAgedAged, 80 and overChildFemaleGenetic LociHaplotypesHumansMaleMethylenetetrahydrofolate Reductase (NADPH2)Middle AgedPrevalencePrimary Health CareMethylenetetrahydrofolate Reductase (NADPH2)MTHFR protein, humanethnic distributionsgenome evolutionhaplotypes

Identifiers

PMID31157538
PMCPMC6630484
OpenAlexW2948542045

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.