Evidence map›Paper›PMID 31177487›Full record

ArticleJournal of thrombosis and thrombolysis2019

Intravascular cells and circulating microparticles induce procoagulant activity via phosphatidylserine exposure in heart failure.

Yan Kou, Lili Zou, Ruipeng Liu, Xinyi Zhao, Ying Wang, Cong Zhang, Zengxiang Dong, Junjie Kou, Yayan Bi, Lu Fu and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of thrombosis and thrombolysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Circulating Extracellular Vesicles in Cardiovascular Disease.International journal of molecular sciences · 2025
    Review
  5. Article
  6. Article
  7. Albumin Is a Component of the Esterase Status of Human Blood Plasma.International journal of molecular sciences · 2023
    Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
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  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yan KouDepartment of Cardiology of the First Hospital, Harbin Medical University, 23 Youzheng Street, Nangang District, Harbin, China.
Lili ZouDepartment of Cardiology of the Second Hospital, Harbin Medical University, Harbin, China.
Ruipeng LiuDepartment of Cardiology of the Second Hospital, Harbin Medical University, Harbin, China.
Xinyi ZhaoDepartment of Cardiology of the Second Hospital, Harbin Medical University, Harbin, China.
Ying WangDepartment of Cardiology of the Second Hospital, Harbin Medical University, Harbin, China.
Cong ZhangDepartment of Ultrasonography of the First Hospital, Harbin Medical University, Harbin, China.
Zengxiang DongDepartment of Cardiology of the First Hospital, Harbin Medical University, 23 Youzheng Street, Nangang District, Harbin, China.
Junjie KouDepartment of Cardiology of the Second Hospital, Harbin Medical University, Harbin, China.
Yayan BiDepartment of Cardiology of the First Hospital, Harbin Medical University, 23 Youzheng Street, Nangang District, Harbin, China.
Lu FuDepartment of Cardiology of the First Hospital, Harbin Medical University, 23 Youzheng Street, Nangang District, Harbin, China. fuluharbin@163.com.
Jialan ShiDepartment of Hematology of the First Hospital, Harbin Medical University, 23 Youzheng Street, Nangang District, Harbin, 150001, China. jialan_shi@hms.harvard.edu.
Harbin Medical University · CNSecond Affiliated Hospital of Harbin Medical University · CNFirst Affiliated Hospital of Harbin Medical University · CN

Funding

National Natural Science Foundation of China 81470301National Natural Science Foundation of China 81670128National Natural Science Foundation of China 81873433
6 · The paper itself

Abstract

Relatively little information is known about the definitive role of phosphatidylserine (PS) in the hypercoagulability of heart failure (HF). Our objectives were to assess the levels of PS exposure on microparticles (MPs) and blood cells (BCs) in each group of HF patients and to evaluate their procoagulant activity (PCA). HF patients in each NYHA functional class II-IV (II n = 30, III n = 30, IV n = 30) and healthy controls (n = 25) were enrolled in the present study. PS exposure on MPs, BCs was analyzed with flow cytometry. MPs were classified based on their cellular origin: platelets (CD41a

Indexed as

AdultAgedBlood CellsBlood CoagulationBlood Coagulation TestsCase-Control StudiesCell-Derived MicroparticlesEndothelial CellsFemaleFlow CytometryHeart FailureHumansMaleMiddle AgedPhosphatidylserinesThrombophiliaPhosphatidylserinesBlood cellsHeart failureMicroparticlesPhosphatidylserineProcoagulant activity

Identifiers

PMID31177487
OpenAlexW2949029817

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.