Evidence map›Paper›PMID 31179276›Full record

ReviewFrontiers in bioengineering and biotechnology2019

Use of Nanoparticles in Tissue Engineering and Regenerative Medicine.

Milad Fathi-Achachelouei, Helena Knopf-Marques, Cristiane Evelise Ribeiro da Silva, Julien Barthès, Erhan Bat, Aysen Tezcaner, Nihal Engin Vrana

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers.

0numbers the graph read from it
0cells of the map it votes in
112citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

112 citing papers in PubMed.

  1. Review
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  6. Stimuli-responsive hybrid materials for 4DMaterials today. Bio · 2025
    Review
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  8. Article
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52 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Milad Fathi-AchacheloueiDepartment of Biomedical Engineering, Middle East Technical University, Ankara, Turkey.
Helena Knopf-MarquesInserm UMR 1121, 11 rue Humann, Strasbourg, France.
Cristiane Evelise Ribeiro da SilvaDepartment of Tests in Materials and Products, Instituto National de Tecnologia, Rio de Janeiro, Brazil.
Julien BarthèsProtip Medical, 8 Place de l'Hôpital, Strasbourg, France.
Erhan BatDepartment of Biomedical Engineering, Middle East Technical University, Ankara, Turkey.
Aysen TezcanerDepartment of Biomedical Engineering, Middle East Technical University, Ankara, Turkey.
Nihal Engin VranaInserm UMR 1121, 11 rue Humann, Strasbourg, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advances in nanoparticle (NP) production and demand for control over nanoscale systems have had significant impact on tissue engineering and regenerative medicine (TERM). NPs with low toxicity, contrasting agent properties, tailorable characteristics, targeted/stimuli-response delivery potential, and precise control over behavior (via external stimuli such as magnetic fields) have made it possible their use for improving engineered tissues and overcoming obstacles in TERM. Functional tissue and organ replacements require a high degree of spatial and temporal control over the biological events and also their real-time monitoring. Presentation and local delivery of bioactive (growth factors, chemokines, inhibitors, cytokines, genes etc.) and contrast agents in a controlled manner are important implements to exert control over and monitor the engineered tissues. This need resulted in utilization of NP based systems in tissue engineering scaffolds for delivery of multiple growth factors, for providing contrast for imaging and also for controlling properties of the scaffolds. Depending on the application, materials, as polymers, metals, ceramics and their different composites can be utilized for production of NPs. In this review, we will cover the use of NP systems in TERM and also provide an outlook for future potential use of such systems.

Indexed as

ceramic nanoparticlesmetallic nanoparticlesnanoparticles in bioinkspolymeric nanoparticlesregenerative medicinetissue engineering

Identifiers

PMID31179276
PMCPMC6543169

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.