Evidence map›Paper›PMID 31200548›Full record

ArticleGenes2019

Identification of Disease Risk DNA Variations is Shaping the Future of Precision Health.

Walid D Fakhouri, Ariadne Letra

Open access · goldAbstract readEditorial
In one paragraph

Article in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Walid D FakhouriCenter for Craniofacial Research, Department of Diagnostic and Biomedical Sciences, School of Dentistry, University of Texas Health Science Center at Houston, Houston, TX 77054, USA. Walid.D.Fakhouri@uth.tmc.edu.ORCID 0000-0002-2199-3828
Ariadne LetraCenter for Craniofacial Research, Department of Diagnostic and Biomedical Sciences, School of Dentistry, University of Texas Health Science Center at Houston, Houston, TX 77054, USA. Ariadne.M.Letra@uth.tmc.edu.ORCID 0000-0002-7197-6735
The University of Texas Health Science Center at Houston · US

Funding

Modeling of pathological significance of non-coding DNA variants in cis-overlapping motifs of p53 and cMycR15GM122030 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI FAKHOURI, WALID D. · 2016 to 2016
$476k
Tooth agenesis as a clinical marker for colon cancerR03DE024596 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI LETRA, ARIADNE M · 2014 to 2015
$228k
6 · The paper itself

Abstract

In recent years, the knowledge generated by decoding the human genome has allowed groundbreaking genetic research to better understand genomic architecture and heritability in healthy and disease states. The vast amount of data generated over time and yet to be generated provides the basis for translational research towards the development of preventive and therapeutic strategies for many conditions. In this special issue, we highlight the discoveries of disease-associated and protective DNA variations in common human diseases and developmental disorders.

Indexed as

Genome-Wide Association StudyGenomicsPrecision MedicineAlternative SplicingDNAGenetic VariationGenome, HumanHumansDNAalternative splicing and mRNA stabilityalternative transcriptional start sitecoding DNA variationsgenomic evolutionnoncoding DNA variationspost-transcriptional and -translational regulation

Identifiers

PMID31200548
PMCPMC6627794
OpenAlexW2952495552

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.