Evidence map›Paper›PMID 31203233›Full record

Trial reportJournal of lipid research2019

Serum apolipoproteins and apolipoprotein-defined lipoprotein subclasses: a hypothesis-generating prospective study of cardiovascular events in T1D.

Arpita Basu, Ionut Bebu, Alicia J Jenkins, Julie A Stoner, Ying Zhang, Richard L Klein, Maria F Lopes-Virella, W Timothy Garvey, Matthew J Budoff, Petar Alaupovic and 2 more

Open access · hybridAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of lipid research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Apolipoprotein C3: form begets function.Journal of lipid research · 2024
    Review
  9. Article
  10. Article
  11. Quartet of APOCs and the Different Roles They Play in Diabetes.Arteriosclerosis, thrombosis, and vascular biology · 2023
    Review
  12. Review
  13. Article
  14. The Remnant Lipoprotein Hypothesis of Diabetes-Associated Cardiovascular Disease.Arteriosclerosis, thrombosis, and vascular biology · 2022
    Review
  15. Observational
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 2 countries.

Arpita BasuDepartment of Kinesiology and Nutrition Sciences, University of Nevada, Las Vegas, Las Vegas, NV.
Ionut BebuThe Biostatistics Center Milken Institute School of Public Health, The George Washington University, Rockville, MD.
Alicia J JenkinsNHMRC Clinical Trials Centre University of Sydney, Camperdown, Sydney, Australia.
Julie A StonerDepartment of Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK.
Ying ZhangDepartment of Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK.
Richard L KleinDivision of Endocrinology Medical University of South Carolina, Charleston, SC.
Maria F Lopes-VirellaDivision of Endocrinology Medical University of South Carolina, Charleston, SC.
W Timothy GarveyDepartment of Nutrition Sciences, University of Alabama at Birmingham and the Birmingham Veterans Affairs Medical Center, Birmingham, AL.
Matthew J BudoffDivision of Cardiology Los Angeles Biomedical Research Institute, Torrance, CA.
Petar AlaupovicOklahoma Medical Research Foundation Oklahoma City, OK.
Timothy J LyonsDivision of Endocrinology Medical University of South Carolina, Charleston, SC lyonstj@musc.edu.
Diabetes Control Complications Trial/Epidemiology of Diabetes Interventions Complications Research Group
Ralph H. Johnson VA Medical Center · USUniversity of Oklahoma Health Sciences Center · USBirmingham VA Medical Center · USGeorge Washington University · USMedical University of South Carolina · USNational Health and Medical Research Council · AUOklahoma Medical Research Foundation · USThe Lundquist Institute · USUniversity of Nevada, Las Vegas · US

Funding

Limited Competition for the Continuation of Epidemiology of Diabetes Interventions and Complications (EDIC) Study Clinical Research Center (Collaborative U01)U01DK094157 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI Ionut Bebu, Barbara Halina Braffett · 2011 to 2026
$97.6M
Vector and Transgenic Mouse CoreP30DK017047 · NIDDK · UNIVERSITY OF WASHINGTON · PI Karin E Bornfeldt · 1986 to 2026
$41.4M
Epidemiology of Diabetes Interventions and Complications Data Coordinating CenterU01DK094176 · NIDDK · GEORGE WASHINGTON UNIVERSITY · PI BEBU, IONUT, BRAFFETT, BARBARA HALINA · 2012 to 2022
$30.8M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Stuart J Frank · 2013 to 2026
$19.5M
Lipoproteins and PEDF in the Vascular Complications of DiabetesR01DK080043 · NIDDK · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI LYONS, TIMOTHY J · 2009 to 2010
$1.4M
NIDDK NIH HHS P30 DK017047NIDDK NIH HHS P30 DK079626NIDDK NIH HHS R01 DK080043NIDDK NIH HHS U01 DK094157NIDDK NIH HHS U01 DK094176
6 · The paper itself

Abstract

APOB, APOC3, and APOE and apolipoprotein-defined lipoprotein subclasses (ADLSs; based on qualitative apolipoprotein complement) have been associated with dyslipidemia and CVD. Our main objective was to define associations of serum apolipoproteins and ADLSs with "any CVD" and "major atherosclerotic cardiovascular events" (MACEs) in a prospective study of T1D. Serum apolipoproteins and ADLSs (14 biomarkers in total) were measured in sera (obtained between 1997 and 2000) from a subset (

Indexed as

AdultApolipoproteinsCardiovascular DiseasesDiabetes ComplicationsDiabetes Mellitus, Type 1FemaleFollow-Up StudiesHumansMaleMiddle AgedProspective StudiesApolipoproteinsapolipoprotein C3major adverse cardiac eventtype 1 diabetes

Identifiers

PMID31203233
PMCPMC6672041
OpenAlexW2950434189

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.