Evidence mapPaperPMID 31207908Full record

Trial reportNutrients2019

Low-Fat Diet Designed for Weight Loss But Not Weight Maintenance Improves Nitric Oxide-Dependent Arteriolar Vasodilation in Obese Adults.

Abeer M Mahmoud, Chueh-Lung Hwang, Mary R Szczurek, Jing-Tan Bian, Christine Ranieri, David D Gutterman, Shane A Phillips

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
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  5. Review
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  15. Differential responses of resistance arterioles to elevated intraluminal pressure in blacks and whites.American journal of physiology. Heart and circulatory physiology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Abeer M MahmoudDepartment of Physical Therapy, University of Illinois at Chicago, Chicago, IL 60612, USA. amahmo4@uic.edu.
Chueh-Lung HwangDepartment of Physical Therapy, University of Illinois at Chicago, Chicago, IL 60612, USA. clhwang@uic.edu.ORCID 0000-0003-2713-4802
Mary R SzczurekDepartment of Physical Therapy, University of Illinois at Chicago, Chicago, IL 60612, USA. mszczurek@uic.edu.
Jing-Tan BianDepartment of Physical Therapy, University of Illinois at Chicago, Chicago, IL 60612, USA. jtbian@uic.edu.
Christine RanieriDepartment of Physical Therapy, University of Illinois at Chicago, Chicago, IL 60612, USA. craneri@uic.edu.
David D GuttermanCardiovascular Center, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA. dgutt@mcw.edu.
Shane A PhillipsDepartment of Physical Therapy, University of Illinois at Chicago, Chicago, IL 60612, USA. shanep@uic.edu.
University of Illinois Chicago · USMedical College of Wisconsin · US

Funding

National Center for Advancing Translational Sciences, National Institutes of Health UL1TR002003NCATS NIH HHS UL1 TR002003NHLBI NIH HHS K99 HL140049NIH HHS HL095701NIH HHS HL130513NIH HHS K99HL140049
6 · The paper itself

Abstract

Obesity is associated with microvascular dysfunction. While low-fat diet improves cardiovascular risk, its contributions on microvascular function, independent of weight loss, is unknown. We tested the hypothesis that nitric oxide (NO)-dependent vasodilation in microvessels is improved by low-fat diets designed for weight loss (LFWL) compared to low-fat weight maintenance (LFWM) diet. Obese adults were randomly assigned to either a LFWL diet (

Indexed as

Diet, Fat-RestrictedObesityAdolescentAdultBody Weight MaintenanceFemaleHumansMaleMicrovesselsMiddle AgedNitric OxideSubcutaneous FatVasodilationWeight LossYoung AdultNitric Oxideacetylcholinecardiovascularflow-induced dilationhypocaloricisocaloriclow-fat dietmicrovasculaturenitric oxideobesityweight loss

Identifiers

PMID31207908
PMCPMC6627594
OpenAlexW2949320346

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.