Evidence map›Paper›PMID 31209053›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

The constrained architecture of mammalian

Fabrice Darbellay, Célia Bochaton, Lucille Lopez-Delisle, Bénédicte Mascrez, Patrick Tschopp, Saskia Delpretti, Jozsef Zakany, Denis Duboule

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Genome-Wide Characterization of theInternational journal of molecular sciences · 2025
    Article
  3. Article
  4. Biology of Hox Genes: Questions and Technological Challenges.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  5. Article
  6. CTCF-dependent insulation ofProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Seeking Sense in the Hox Gene Cluster.Journal of developmental biology · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Sequential inGenes & development · 2021
    Article
  15. Dbx2 regulation in limbs suggests interTAD sharing of enhancers.Developmental dynamics : an official publication of the American Association of Anatomists · 2021
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fabrice DarbellaySchool of Life Sciences, Federal Institute of Technology, Lausanne, 1015 Lausanne, Switzerland.ORCID 0000-0001-6942-3325
Célia BochatonSchool of Life Sciences, Federal Institute of Technology, Lausanne, 1015 Lausanne, Switzerland.
Lucille Lopez-DelisleSchool of Life Sciences, Federal Institute of Technology, Lausanne, 1015 Lausanne, Switzerland.ORCID 0000-0002-1964-4960
Bénédicte MascrezDepartment of Genetics and Evolution, University of Geneva, 1211 Geneva 4, Switzerland.
Patrick TschoppDepartment of Genetics and Evolution, University of Geneva, 1211 Geneva 4, Switzerland.
Saskia DelprettiSchool of Life Sciences, Federal Institute of Technology, Lausanne, 1015 Lausanne, Switzerland.
Jozsef ZakanyDepartment of Genetics and Evolution, University of Geneva, 1211 Geneva 4, Switzerland.
Denis DubouleSchool of Life Sciences, Federal Institute of Technology, Lausanne, 1015 Lausanne, Switzerland; Denis.Duboule@epfl.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In many animal species with a bilateral symmetry,

Indexed as

AllelesAnimalsCCCTC-Binding FactorCRISPR-Associated Protein 9CRISPR-Cas SystemsGene EditingGene Expression RegulationGenes, HomeoboxGenetic LociHomeodomain ProteinsMammalsMiceMultigene FamilySequence InversionTranscription FactorsTranscription, GeneticCCCTC-Binding FactorCRISPR-Associated Protein 9Ctcf protein, mouseHomeodomain ProteinsHoxd11 protein, mouseHoxd12 protein, mouseTranscription FactorsCRISPR-Cas9CTCFHoxPolycombtranscription

Identifiers

PMID31209053
PMCPMC6613147

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.