Evidence map›Paper›PMID 31209456›Full record

SynthesisAdvances in nutrition (Bethesda, Md.)2019

The Mediterranean, Dietary Approaches to Stop Hypertension (DASH), and Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diets Are Associated with Less Cognitive Decline and a Lower Risk of Alzheimer's Disease-A Review.

Annelien C van den Brink, Elske M Brouwer-Brolsma, Agnes A M Berendsen, Ondine van de Rest

Registry-linked trialOpen access · hybridAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Advances in nutrition (Bethesda, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06942780 (Preliminary Efficacy and Feasibility Analysis of Cognitive Training, Group Social Activities, Physical Exercise, and MIND Diet in Patients With Mild Cognitive Impairment), which is not on this map. Cited by 314 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
314citing papers in PubMed, 9 pooled it
44.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06942780 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Preliminary Efficacy and Feasibility Analysis of Cognitive Training, Group Social Activities, Physical Exercise, and MIND Diet in Patients With Mild Cognitive Impairment

TypeinterventionalSponsorXuanwu Hospital, BeijingRan2025 to 2025Enrolled30ConditionsMild Cognitive Impairment (MCI)ArmsExercise intervention, Social intervention, Dietary intervention, Cognitive intervention, Health Education Manual
3 · Its place in the literature

Who cites it

314 citing papers in PubMed, 9 syntheses or guidelines pooled it, 541 citations in OpenAlex.

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  17. [Modifiable risk and protective factors for dementia: an overview of established and emerging evidence].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2026
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254 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Annelien C van den BrinkDivision of Human Nutrition and Health, Wageningen University, Wageningen, Netherlands.
Elske M Brouwer-BrolsmaDivision of Human Nutrition and Health, Wageningen University, Wageningen, Netherlands.
Agnes A M BerendsenDivision of Human Nutrition and Health, Wageningen University, Wageningen, Netherlands.
Ondine van de RestDivision of Human Nutrition and Health, Wageningen University, Wageningen, Netherlands.
Wageningen University & Research · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As there is currently no cure for dementia, there is an urgent need for preventive strategies. The current review provides an overview of the existing evidence examining the associations of the Mediterranean, Dietary Approaches to Stop Hypertension (DASH), and Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diets and their dietary components with cognitive decline, dementia, and Alzheimer's disease (AD). A systematic search was conducted within Ovid Medline for studies published up to 27 March 2019 and reference lists from existing reviews and select articles were examined to supplement the electronic search results. In total, 56 articles were included. Higher adherence to the Mediterranean diet was associated with better cognitive scores in 9 of 12 cross-sectional studies, 17 of 25 longitudinal studies, and 1 of 3 trials. Higher adherence to the DASH diet was associated with better cognitive function in 1 cross-sectional study, 2 of 5 longitudinal studies, and 1 trial. Higher adherence to the MIND diet was associated with better cognitive scores in 1 cross-sectional study and 2 of 3 longitudinal studies. Evidence on the association of these dietary patterns with dementia in general was limited. However, higher adherence to the Mediterranean diet was associated with a lower risk of AD in 1 case-control study and 6 of 8 longitudinal studies. Moreover, higher adherence to the DASH or MIND diets was associated with a lower AD risk in 1 longitudinal study. With respect to the components of these dietary patterns, olive oil may be associated with less cognitive decline. In conclusion, current scientific evidence suggests that higher adherence to the Mediterranean, DASH, or MIND diets is associated with less cognitive decline and a lower risk of AD, where the strongest associations are observed for the MIND diet.

Indexed as

Dietary Approaches To Stop HypertensionDiet, MediterraneanAdultAgedAged, 80 and overAlzheimer DiseaseCase-Control StudiesCognitive DysfunctionCross-Sectional StudiesFemaleHumansLongitudinal StudiesMaleMEDLINEMiddle AgedNeurodegenerative DiseasesAlzheimer's diseasecognitioncognitive declineDASHdementiadietary componentsdietary patternsMediterraneanMINDnutrition

Identifiers

PMID31209456
PMCPMC6855954
OpenAlexW2951769614

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.