Evidence map›Paper›PMID 31218482›Full record

ArticleJournal of thrombosis and thrombolysis2019

Gender differences in thrombogenicity among patients with angina and non-obstructive coronary artery disease.

Rahul Chaudhary, Ajaypaul Sukhi, Rohit Chaudhary, Manila Jindal, Ankit Vyas, Amit Rout, Kevin Bliden, Udaya Tantry, Paul Gurbel

2 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in Journal of thrombosis and thrombolysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06675994 not yet recruitingstarted 2024, after this paper: background citation

Evaluation of PCSK9 Enzyme in Non-Cholesterol Biological Pathways: In Vitro Demonstration of Direct Platelet-Related Effects of PCSK9 Enzyme

Ran2024Enrolled80Registered outcomes4Posted comparisons0ConditionsDiabetes, Family History of Cerebrovascular Disease, Family History of Coronary Artery Disease, Family History of Peripheral Artery DiseaseArmsPCSK9 Antibody, PCSK9 Enzyme
PMID 26896437PMID 27810295PMID 16286165PMID 16554528PMID 20124137PMID 25332180PMID 26092101PMID 31511398PMID 32252393PMID 33026143PMID 34681838PMID 35078371other papers from this trial
Open the trial in the graph
NCT01276678 unknown statusnot on this map

Multi-Analyte, Genetic, and Thrombogenic Markers of Atherosclerosis (The MAGMA STUDY)

TypeobservationalSponsorLifeBridge HealthRan2010 to 2014Enrolled1,300ConditionsCoronary Artery Disease
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Observational
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  10. "International journal of molecular sciences · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Rahul ChaudharySinai Hospital of Baltimore, Baltimore, MD, USA.
Ajaypaul SukhiSinai Hospital of Baltimore, Baltimore, MD, USA.
Rohit ChaudharyPeter Lee Associates, Sydney, Australia.
Manila JindalInova Center for Thrombosis Research and Drug Development, Inova Heart and Vascular Institute, Fairfax, VA, USA.
Ankit VyasInova Center for Thrombosis Research and Drug Development, Inova Heart and Vascular Institute, Fairfax, VA, USA.
Amit RoutSinai Hospital of Baltimore, Baltimore, MD, USA.
Kevin BlidenInova Center for Thrombosis Research and Drug Development, Inova Heart and Vascular Institute, Fairfax, VA, USA.
Udaya TantryPlatelet and Thrombosis Research, Baltimore, MD, USA.
Paul GurbelInterventional Cardiology and Cardiovascular Medicine Research, Inova Center for Thrombosis Research and Drug Development, Inova Heart and Vascular Institute, 3300 Gallows Road, Falls Church, VA, 22042, USA. Paul.Gurbel@inova.org.
Sinai Hospital · USMayo Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Women more often present with angina and non-obstructive coronary artery disease (ANOCA) and have poorer clinical outcomes than men. These findings may be related to sex associated differences in inflammation and thrombogenicity. Consecutive patients (n = 134) with ANOCA (luminal diameter stenosis < 50%) undergoing elective cardiac catheterization were included in post hoc analysis of Multi-Analyte, thrombogenic, and Genetic Markers of Atherosclerosis (MAGMA, NCT01276678) study. Patients with prior revascularization, coronary artery bypass grafting or myocardial infarction were excluded. Blood for thromboelastography, oxidized LDL β2-glycoprotein complex (AtherOx), oxidized-LDL, lipid profile, and urine for 11-dehydrothromboxane B

Indexed as

Sex FactorsAgedAngina PectorisBiomarkersBlood CoagulationBlood Coagulation TestsCoronary Artery DiseaseFemaleHumansInflammationMaleMiddle AgedRisk FactorsThrombelastographyThrombosisBiomarkersANOCACardiovascular outcomesCoronary artery diseaseNon-obstructive CADTEGThrombogenicity

Identifiers

PMID31218482
OpenAlexW2952148732

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.