Evidence map›Paper›PMID 31219005›Full record

ArticleThe American journal of tropical medicine and hygiene2019

A Combination of Itraconazole and Amiodarone Is Highly Effective against

Gabriele Sass, Roy T Madigan, Lydia-Marie Joubert, Adriana Bozzi, Nazish Sayed, Joseph C Wu, David A Stevens

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Repurposing of Amiodarone for treatment of muscle phase of experimental trichinellosis spiralis.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025
    Article
  5. Article
  6. Article
  7. Benznidazole and amiodarone combined treatment attenuates cytoskeletal damage inFrontiers in cellular and infection microbiology · 2022
    Article
  8. Article
  9. Review
  10. Review on Experimental Treatment Strategies AgainstJournal of experimental pharmacology · 2021
    Review
  11. Review
  12. Vismione B Interferes withThe American journal of tropical medicine and hygiene · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Gabriele SassCalifornia Institute for Medical Research, San Jose, California.
Roy T MadiganAnimal Hospital of Smithson Valley, Spring Branch, Texas.
Lydia-Marie JoubertEM Unit, Central Analytical Facilities, Stellenbosch University, Stellenbosch, South Africa.
Adriana BozziCalifornia Institute for Medical Research, San Jose, California.
Nazish SayedSchool of Medicine, Cardiovascular Institute, Stanford University, Stanford, California.
Joseph C WuSchool of Medicine, Cardiovascular Institute, Stanford University, Stanford, California.
David A StevensDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California.
California Institute for Medical Research · USCardiovascular Institute of the South · USFundação Oswaldo Cruz · BRStanford University · USStellenbosch University · ZA

Funding

T32 Training Program in Mechanisms and Innovation in Vascular DiseaseT32HL098049 · NHLBI · STANFORD UNIVERSITY · PI Nicholas James Leeper, Philip S Tsao · 2010 to 2026
$6.3M
Human iPSCs for Elucidating Intercellular Crosstalk Signaling in Dilated CardiomyopathyR01HL141371 · NHLBI · STANFORD UNIVERSITY · PI WONG, WING H., WU, JOSEPH C. · 2018 to 2025
$6.2M
Modeling Tyrosine Kinase Inhibitor-Induced Vascular Dysfunction Using Human iPSCsR01HL141851 · NHLBI · STANFORD UNIVERSITY · PI WONG, WING H., WU, JOSEPH C. · 2018 to 2025
$5.7M
Modeling Endothelial Dysfunction in LMNA-related Dilated CardiomyopathyK01HL135455 · NHLBI · STANFORD UNIVERSITY · PI SAYED, NAZISH · 2017 to 2021
$828k
NHLBI NIH HHS K01 HL135455NHLBI NIH HHS R01 HL141371NHLBI NIH HHS R01 HL141851
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug RepositioningAmiodaroneAnimalsChlorocebus aethiopsHumansItraconazoleMyocytes, CardiacStem CellsTrypanocidal AgentsTrypanosoma cruziVero CellsAmiodaroneItraconazoleTrypanocidal Agents

Identifiers

PMID31219005
PMCPMC6685576
OpenAlexW3021697077

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.