Evidence map›Paper›PMID 31219365›Full record

ReviewExpert review of anticancer therapy2019

Recent advances with cyclin-dependent kinase inhibitors: therapeutic agents for breast cancer and their role in immuno-oncology.

Gabriele Di Sante, Jessica Pagé, Xuanmao Jiao, Omar Nawab, Massimo Cristofanilli, Emmanuel Skordalakes, Richard G Pestell

Open access · bronzeAbstract readReview
In one paragraph

Review in Expert review of anticancer therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pairwise analysis of plasma cell-free DNA before and after palliative second-line paclitaxel plus ramucirumab treatment in patients with metastatic gastric cancer.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2025
    Article
  4. Targeting WEE1 Kinase for Breast Cancer Therapeutics: An Update.International journal of molecular sciences · 2025
    Review
  5. Article
  6. Article
  7. Synthesis and Preclinical Evaluation of NovelACS medicinal chemistry letters · 2024
    Article
  8. Article
  9. Review
  10. FBXW7 in breast cancer: mechanism of action and therapeutic potential.Journal of experimental & clinical cancer research : CR · 2023
    Review
  11. Article
  12. European journal of breast health · 2023
    Article
  13. Review
  14. Article
  15. Review
  16. High-LevelOphthalmology science · 2022
    Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Gabriele Di Santea Pennsylvania Cancer and Regenerative Medicine Research Center , Baruch S. Blumberg Institute, Pennsylvania Biotechnology Center , Wynnewood , PA , USA.
Jessica Pagéb Xavier University School of Medicine , Woodbury , NY , USA.
Xuanmao Jiaoa Pennsylvania Cancer and Regenerative Medicine Research Center , Baruch S. Blumberg Institute, Pennsylvania Biotechnology Center , Wynnewood , PA , USA.
Omar Nawaba Pennsylvania Cancer and Regenerative Medicine Research Center , Baruch S. Blumberg Institute, Pennsylvania Biotechnology Center , Wynnewood , PA , USA.
Massimo Cristofanillic Department of Medicine-Hematology and Oncology, Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine , Northwestern University , Chicago , IL , USA.
Emmanuel Skordalakesd Wistar Institute , Philadelphia , PA , USA.
Richard G Pestella Pennsylvania Cancer and Regenerative Medicine Research Center , Baruch S. Blumberg Institute, Pennsylvania Biotechnology Center , Wynnewood , PA , USA.
Baruch S. Blumberg Institute · USXavier University · USNorthwestern University · USThe Wistar Institute · US

Funding

Tumor Microenvironment and MetastasisP30CA010815 · NCI · WISTAR INSTITUTE · PI Aaron Robert Goldman · 1985 to 2026
$75.9M
DACH1/Eya Cell fate determination factor and mammary tumorigenesisR01CA132115 · NCI · THOMAS JEFFERSON UNIVERSITY · PI PESTELL, RICHARD G · 2009 to 2018
$3.1M
NCI NIH HHS P30 CA010815NCI NIH HHS R01 CA132115
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntineoplastic AgentsBreast NeoplasmsCell CycleCyclin-Dependent KinasesDisease ProgressionFemaleHumansNeoplasm InvasivenessProtein Kinase InhibitorsAntineoplastic AgentsCyclin-Dependent KinasesProtein Kinase InhibitorsBreast cancerCDK inhibitorschromosomal instabilityclinical trialcyclin D1

Identifiers

PMID31219365
PMCPMC6834352
OpenAlexW2950808387

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.