Evidence map›Paper›PMID 31220087›Full record

Trial reportPloS one2019

Development and validation of quick Acute Kidney Injury-score (q-AKI) to predict acute kidney injury at admission to a multidisciplinary intensive care unit.

Fiorenza Ferrari, Mariangela Valentina Puci, Ottavia Eleonora Ferraro, Gregorio Romero-González, Faeq Husain-Syed, Lilia Rizo-Topete, Mara Senzolo, Anna Lorenzin, Eva Muraro, Antonio Baracca and 12 more

Abstract readClinical TrialValidation Study
In one paragraph

Trial report in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
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  5. [Predictive scale of acute kidney failure in sepsis (ARMO)].Revista de salud publica (Bogota, Colombia) · 2023
    Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Fiorenza FerrariInternational Renal Research Institute of Vicenza (IRRIV) and Department of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, Viale Rodolfi, Vicenza, Italy.ORCID 0000-0001-6001-7072
Mariangela Valentina PuciDepartment of Public Health, Experimental and Forensic Medicine, Unit of Biostatistics and Clinical Epidemiology, University of Pavia - Via Forlanini, Pavia, Italy.
Ottavia Eleonora FerraroDepartment of Public Health, Experimental and Forensic Medicine, Unit of Biostatistics and Clinical Epidemiology, University of Pavia - Via Forlanini, Pavia, Italy.
Gregorio Romero-GonzálezInternational Renal Research Institute of Vicenza (IRRIV) and Department of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, Viale Rodolfi, Vicenza, Italy.
Faeq Husain-SyedInternational Renal Research Institute of Vicenza (IRRIV) and Department of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, Viale Rodolfi, Vicenza, Italy.
Lilia Rizo-TopeteInternational Renal Research Institute of Vicenza (IRRIV) and Department of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, Viale Rodolfi, Vicenza, Italy.
Mara SenzoloInternational Renal Research Institute of Vicenza (IRRIV) and Department of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, Viale Rodolfi, Vicenza, Italy.
Anna LorenzinInternational Renal Research Institute of Vicenza (IRRIV) and Department of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, Viale Rodolfi, Vicenza, Italy.
Eva MuraroInternational Renal Research Institute of Vicenza (IRRIV) and Department of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, Viale Rodolfi, Vicenza, Italy.
Antonio BaraccaabcGo.S.r.l. Viale Merello, Cagliari, Italy.
Mara Serrano-SotoInternational Renal Research Institute of Vicenza (IRRIV) and Department of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, Viale Rodolfi, Vicenza, Italy.
Alejandra Molano TriviñoInternational Renal Research Institute of Vicenza (IRRIV) and Department of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, Viale Rodolfi, Vicenza, Italy.
Ana Coutinho CastroInternational Renal Research Institute of Vicenza (IRRIV) and Department of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, Viale Rodolfi, Vicenza, Italy.
Massimo De CalInternational Renal Research Institute of Vicenza (IRRIV) and Department of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, Viale Rodolfi, Vicenza, Italy.
Valentina CorradiInternational Renal Research Institute of Vicenza (IRRIV) and Department of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, Viale Rodolfi, Vicenza, Italy.
Alessandra BrendolanInternational Renal Research Institute of Vicenza (IRRIV) and Department of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, Viale Rodolfi, Vicenza, Italy.
Marta ScarpaInternational Renal Research Institute of Vicenza (IRRIV) and Department of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, Viale Rodolfi, Vicenza, Italy.
Maria Rosa CartaDepartment of Laboratory Medicine, San Bortolo Hospital, Vicenza, Italy.
Davide GiavarinaDepartment of Laboratory Medicine, San Bortolo Hospital, Vicenza, Italy.
Raffaele BonatoIntensive Care Unit, San Bortolo Hospital, Viale Rodolfi, Vicenza, Italy.
Giorgio Antonio IottiIntensive Care Unit, I.R.C.C.S. Policlinico San Matteo, Viale Golgi, Pavia, Italy.
Claudio RoncoInternational Renal Research Institute of Vicenza (IRRIV) and Department of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, Viale Rodolfi, Vicenza, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AKI is associated with increased risk of death, prolonged length of stay and development of de-novo chronic kidney disease. The aim of our study is the development and validation of prediction models to identify the risk of AKI in ICU patients up to 7 days. We retrospectively recruited 692 consecutive patients admitted to the ICU at San Bortolo Hospital (Vicenza, Italy) from 1 June 2016 to 31 March 2017: 455 patients were treated as the derivation group and 237 as the validation group. Candidate variables were selected based on a literature review and expert opinion. Admission eGFR< 90 ml/min /1.73 mq (OR 2.78; 95% CI 1.78-4.35; p<0.001); SOFAcv ≥ 2 (OR 2.23; 95% CI 1.48-3.37; p<0.001); lactate ≥ 2 mmol/L (OR 1.81; 95% CI 1.19-2.74; p = 0.005) and (TIMP-2)•(IGFBP7) ≥ 0.3 (OR 1.65; 95% CI 1.08-2.52; p = 0.019) were significantly associated with AKI. For the q-AKI score, we stratified patients into different AKI Risk score levels: 0-2; 3-4; 5-6; 7-8 and 9-10. In both cohorts, we observed that the proportion of AKI patients was higher in the higher score levels.

Indexed as

Acute Kidney InjuryCritical CareGlomerular Filtration RateIntensive Care UnitsRegistriesAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective Studies

Identifiers

PMID31220087
PMCPMC6586286

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.