Evidence map›Paper›PMID 31221698›Full record

Trial reportDiabetes care2019

Aerobic Fitness and Adherence to Guideline-Recommended Minimum Physical Activity Among Ambulatory Patients With Type 2 Diabetes Mellitus.

Jennifer L Jarvie, Ambarish Pandey, Colby R Ayers, Jonathan M McGavock, Martin Sénéchal, Jarett D Berry, Kershaw V Patel, Darren K McGuire

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Diabetes care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00424762 (Effect of Rosiglitazone Versus Placebo on Cardiovascular Performance and Myocardial Triglyceride), which is not on this map. Cited by 40 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 5 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00424762 phase4completednot on this map

Effect of Rosiglitazone Versus Placebo on Cardiovascular Performance and Myocardial Triglyceride

TypeinterventionalSponsorUniversity of Texas Southwestern Medical CenterRan2005 to 2007Enrolled150ConditionsDiabetes Mellitus, Type 2Armsrosiglitazone, placebo
3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 5 syntheses or guidelines pooled it, 75 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Jennifer L JarvieDivision of Cardiology, University of Colorado School of Medicine, Aurora, CO.
Ambarish PandeyDivision of Cardiology, University of Texas Southwestern Medical Center, Dallas, TX.
Colby R AyersDepartment of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX.
Jonathan M McGavockManitoba Institute of Child Health, Winnipeg, Manitoba, Canada.
Martin SénéchalCardio-Metabolic Exercise and Lifestyle Laboratory, Fredericton, New Brunswick, Canada.
Jarett D BerryDivision of Cardiology, University of Texas Southwestern Medical Center, Dallas, TX.
Kershaw V PatelDivision of Cardiology, University of Texas Southwestern Medical Center, Dallas, TX.
Darren K McGuireDivision of Cardiology, University of Texas Southwestern Medical Center, Dallas, TX darren.mcguire@utsouthwestern.edu.ORCID 0000-0002-6412-7989
The University of Texas Southwestern Medical Center · USChildren's Hospital Research Institute of Manitoba · CAUniversity of Colorado Denver · USUniversity of New Brunswick · CA

Funding

XU 40468 IN HYPERCHOLESTEROLEMIAM01RR000633 · NCRR · UT SOUTHWESTERN MEDICAL CENTER · PI GINSBURG, CHARLES · 1985 to 2007
$21.0M
Magnetic Resonance Imaging of Carotid Artery Subclincal AtherosclerosisK23HL092229 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI BERRY, JARETT D · 2009 to 2013
$661k
NCRR NIH HHS M01 RR000633NHLBI NIH HHS K23 HL092229
6 · The paper itself

Abstract

objectiveLifestyle intervention remains the cornerstone of management of type 2 diabetes mellitus (T2DM). However, adherence to physical activity (PA) recommendations and the impact of that adherence on cardiorespiratory fitness in this population have been poorly described. We sought to investigate adherence to PA recommendations and its association with cardiorespiratory fitness in a population of patients with T2DM. RESEARCH DESIGN AND

methodsA cross-sectional analysis of baseline data from a randomized clinical trial (NCT00424762) was performed. A total of 150 individuals with medically treated T2DM and atherosclerotic cardiovascular disease (ASCVD) or risk factors for ASCVD were recruited from outpatient clinics at a single academic medical center. All individuals underwent a graded maximal exercise treadmill test to exhaustion with breath-by-breath gas exchange analysis to determine VO

resultsParticipants had a mean ± SD age of 54.9 ± 9.0 years; 41% were women, 40% were black, and 21% were Hispanic. The mean HbA

conclusionsOn average, patients with T2DM who have or are at risk for ASCVD report low levels of PA and have low measured cardiopulmonary fitness. This underscores the importance of continued efforts to close this therapeutic gap.

Indexed as

AdultAgedAmbulatory CareAtherosclerosisCardiorespiratory FitnessCardiovascular SystemCombined Modality TherapyCross-Sectional StudiesDiabetes Mellitus, Type 2Diabetic AngiopathiesExerciseExercise TestFemaleGuideline AdherenceHumansLife StyleRosiglitazone

Identifiers

PMID31221698
PMCPMC6609956
OpenAlexW2945092888

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.