ArticleBiology of sport2019
Effect of exercise on glucose variability in healthy subjects: randomized crossover trial.
Article in Biology of sport, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02262208 (Exercise as a Tool for Studying the Mechanisms and Applicability of Glycemic Variability in Individuals With and Without Type 2 Diabetes Mellitus), which is not on this map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Exercise as a Tool for Studying the Mechanisms and Applicability of Glycemic Variability in Individuals With and Without Type 2 Diabetes Mellitus
Who cites it
15 citing papers in PubMed, 19 citations in OpenAlex.
- Efficiency of an mHealth App and Chest-Wearable Remote Exercise Monitoring Intervention in Patients With Type 2 Diabetes: A Prospective, Multicenter Randomized Controlled Trial.JMIR mHealth and uHealth · 2021Trial
- Impact of Glycemic Trajectory and Variability on Ischemic Stroke Prognosis and Exploration of Its Mechanisms: A Comprehensive Review.Healthcare (Basel, Switzerland) · 2026Review
- Use of Continuous Glucose Monitors in Exercise Research Studies-A Scoping Review on Study Characteristics and Common Practices.Sports (Basel, Switzerland) · 2026Review
- Effects of Physical Exercise on Cardiometabolic Health in Individuals with Autism Spectrum Disorder: A Systematic Review.Healthcare (Basel, Switzerland) · 2025Review
- Continuous Glucose Profiles in Healthy People With Fixed Meal Times and Under Everyday Life Conditions.Journal of diabetes science and technology · 2024Article
- Associations between glycemic variability, sleep quality, and daily steps in subjects without diabetes using wearable devices.Metabolism open · 2023Article
- Oscillating Glucose Induces the Increase in Inflammatory Stress through Ninjurin-1 Up-Regulation and Stimulation of Transport Proteins in Human Endothelial Cells.Biomolecules · 2023Article
- Comparative effectiveness of playing golf to Nordic walking and walking on acute physiological effects on cardiometabolic markers in healthy older adults: a randomised cross-over study.BMJ open sport & exercise medicine · 2023Article
- Flash glucose monitoring system in special situations.Archives of endocrinology and metabolism · 2022Review
- Maintenance of plasma glucose variability after an acute session of aerobic exercise despite changes in insulin and glucagon-like peptide-1 levels in type 2 diabetes.Archives of endocrinology and metabolism · 2022Article
- Associations Between Device-Measured Physical Activity and Glycemic Control and Variability Indices Under Free-Living Conditions.Diabetes technology & therapeutics · 2022Article
- Glycemic Variability Within 1 Year Following Surgery for Stage II-III Colon Cancer.Biological research for nursing · 2022Article
- Glycemic variability: Importance, relationship with physical activity, and the influence of exercise.Sports medicine and health science · 2021Review
- Comprehensive elaboration of glycemic variability in diabetic macrovascular and microvascular complications.Cardiovascular diabetology · 2021Review
- Glycemic variability: adverse clinical outcomes and how to improve it?Cardiovascular diabetology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to evaluate the acute effect of aerobic (AER) and eccentric (ECC) exercise on glucose variability, correlating it with circulating markers of inflammation and oxidative stress in healthy subjects. Sixteen healthy subjects (32 ± 12 years old) wore a continuous glucose monitoring system for three days. Participants randomly performed single AER and ECC exercise sessions. Glucose variability was evaluated by glucose variance (VAR), glucose coefficient of variation (CV%) and glucose standard deviation (SD). Blood samples were collected to evaluate inflammatory and oxidative stress markers. When compared with the pre-exercise period of 0-6 h, all the indices of glucose variability presented comparable reductions 12-18 h after both exercises (∆AER: VAR= 151.5, ∆CV% = 0.55 and ∆SD = 3.1 and ECC: ∆VAR = 221.2 , ∆CV% = 3.7 and ∆SD = 6.5). Increased interleukin-6 (IL-6) levels after AER (68.5%) and ECC (30.8%) (P<0.001) were observed, with no differences between sessions (P = 0.459). Uric acid levels were increased after exercise sessions (3% in AER and 4% in ECC, P = 0.001). In conclusion, both AER and ECC exercise sessions reduced glucose variability in healthy individuals. Inflammatory cytokines, such as IL-6, and stress oxidative markers might play a role in underlying mechanisms modulating the glucose variability responses to exercise (clinicalTrials.gov NCT02262208).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.