Evidence map›Paper›PMID 31229524›Full record

ArticleProstaglandins & other lipid mediators2019

Prostaglandin E

Timothy D Bryson, Jacob Ross, Edward Peterson, Pamela Harding

Open access · greenAbstract read
In one paragraph

Article in Prostaglandins & other lipid mediators, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Prostaglandin EEXCLI journal · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. The deleterious role of the prostaglandin EAmerican journal of physiology. Heart and circulatory physiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Timothy D BrysonHypertension & Vascular Research Division, Dept. Internal Medicine, USA; Dept. of Physiology, Wayne State University School of Medicine, USA.
Jacob RossHypertension & Vascular Research Division, Dept. Internal Medicine, USA.
Edward PetersonDept. of Public Health Sciences Henry Ford Hospital, Detroit, Michigan, USA.
Pamela HardingHypertension & Vascular Research Division, Dept. Internal Medicine, USA; Dept. of Physiology, Wayne State University School of Medicine, USA. Electronic address: phardin1@hfhs.org.
Hypertension Institute · USHenry Ford Hospital · USWayne State University · US

Funding

VASOACTIVE HORMONES IN THE REGULATION OF BLOOD PRESSUREP01HL028982 · NHLBI · HENRY FORD HOSPITAL · PI ORTIZ, PABLO A. · 1985 to 2017
$39.8M
Detroit Cardiovascular Training ProgramT32HL120822 · NHLBI · WAYNE STATE UNIVERSITY · PI LEVY, PHILLIP DAVID · 2014 to 2023
$1.8M
NHLBI NIH HHS P01 HL028982NHLBI NIH HHS T32 HL120822
6 · The paper itself

Abstract

backgroundProstaglandin E2 (PGE METHODS AND

resultsOur hypothesis was tested using isolated mouse adult ventricular fibroblasts (AVF) treated with LPS. Pre-treatment of the cells with PGE

conclusionExogenous treatment of PGE

Indexed as

AnimalsDinoprostoneFibroblastsGene Expression RegulationLipopolysaccharidesMaleMiceMice, Inbred C57BLMonocyte Chemoattractant ProteinsMyocardiumNF-kappa BPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktReceptors, Prostaglandin E, EP4 SubtypeRNA, MessengerSignal TransductionCcl12 protein, mouseDinoprostoneLipopolysaccharidesMonocyte Chemoattractant ProteinsNF-kappa BPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktReceptors, Prostaglandin E, EP4 SubtypeRNA, MessengerChemokineE2EP4FibroblastHeartInflammationProstaglandin

Identifiers

PMID31229524
PMCPMC6778017
OpenAlexW2949218444

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.