Evidence map›Paper›PMID 31230490›Full record

ArticleApplied neuropsychology. Adult

Normative data stratified by age and education for a Spanish neuropsychological test battery: Results from the Colombian Alzheimer's prevention initiative registry.

Valeria L Torres, Clara Vila-Castelar, Yamile Bocanegra, Ana Baena, Edmarie Guzmán-Vélez, Daniel C Aguirre-Acevedo, Victoria Tirado, Claudia Munoz, Eliana Henao, Sonia Moreno and 10 more

Open access · greenAbstract read
In one paragraph

Article in Applied neuropsychology. Adult. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. The New England journal of medicine · 2024
    Article
  7. Plasma p-tau217 predicts in vivo brain pathology and cognition in autosomal dominant Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Association Between Visual Memory andJournal of the International Neuropsychological Society : JINS · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 2 countries.

Valeria L TorresDepartment of Psychology, Florida Atlantic University, Boca Raton, Florida, USA.
Clara Vila-CastelarDepartment of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachussetts, USA.
Yamile BocanegraGrupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
Ana BaenaGrupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
Edmarie Guzmán-VélezDepartment of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachussetts, USA.
Daniel C Aguirre-AcevedoGrupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
Victoria TiradoGrupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
Claudia MunozGrupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
Eliana HenaoGrupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
Sonia MorenoGrupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
Margarita GiraldoGrupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
Natalia AcostaGrupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
Silvia Rios RomenetsGrupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
Jessica B LangbaumBanner Alzheimer's Institute, Phoenix, Arizona, USA.
William ChoGenentech, South San Fransisco, California, USA.
Eric M ReimanBanner Alzheimer's Institute, Phoenix, Arizona, USA.
Pierre N TariotBanner Alzheimer's Institute, Phoenix, Arizona, USA.
Monica RosselliDepartment of Psychology, Florida Atlantic University, Boca Raton, Florida, USA.
Yakeel T QuirozDepartment of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachussetts, USA.
Francisco LoperaGrupo de Neurociencias de Antioquia, Universidad de Antioquia, Medellín, Colombia.
Universidad de Antioquia · COBanner Alzheimer’s InstituteFlorida Atlantic University · USMassachusetts General Hospital · USAlzheimer's Association · USHarvard University · US

Funding

Research Education ComponentP30AG019610 · NIA · SUN HEALTH RESEARCH INSTITUTE · PI ALEXANDER, GENE E · 2001 to 2020
$32.5M
Research Education ComponentP30AG072980 · NIA · BANNER HEALTH · PI ALIREZA ATRI · 2021 to 2026
$24.9M
Alzheimer's Prevention InitiativeRF1AG041705 · NIA · BANNER ALZHEIMER'S INSTITUTE · PI LOPERA, FRANCISCO, REIMAN, ERIC MICHAEL · 2012 to 2012
$15.3M
Alzheimer's Prevention Initiative ADAD Colombia TrialR01AG055444 · NIA · BANNER HEALTH · PI LOPERA, FRANCISCO, REIMAN, ERIC MICHAEL · 2017 to 2022
$14.9M
Relationship between tau pathology and cognitive impairment in autosomal dominant Alzheimer's diseaseR01AG054671 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI QUIROZ, YAKEEL T. · 2017 to 2021
$3.8M
Memory network dysfunction as an early marker of preclinical Alzheimer's DiseaseDP5OD019833 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI QUIROZ, YAKEEL T. · 2014 to 2018
$2.3M
Aerobic fitness as a modifier of neurodegeneration and cognitive decline in preclinical Alzheimer's diseaseK23AG061276 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI GUZMÁN-VÉLEZ, EDMARIE · 2019 to 2023
$881k
NIA NIH HHS K23 AG061276NIA NIH HHS P30 AG019610NIA NIH HHS P30 AG072980NIA NIH HHS R01 AG054671NIA NIH HHS R01 AG055444NIA NIH HHS RF1 AG041705NIH HHS DP5 OD019833
6 · The paper itself

Abstract

Neuropsychologists continue to face challenges when assessing Spanish-speaking individuals due to limited availability of normative data. We developed comprehensive normative data stratified by age and education for a Spanish neuropsychological test battery used by the Grupo de Neurociencias de Antioquia (Colombia) and the Colombian Alzheimer's Prevention Initiative Registry, which have followed large families at risk for autosomal-dominant Alzheimer's disease (ADAD) since the 1990s. Approximately 75% of these individuals are cognitively-unimpaired and are not genetically predisposed to develop ADAD. We conducted a retrospective study on neuropsychological evaluations from 2,673 cognitively unimpaired individuals (56% female), with ages ranging from 18 to 86 years and education from 1 to 25 years. Neuropsychological measures included the Consortium to Establish a Registry for Alzheimer's Disease-Colombia, and other multidomain Spanish tests. We examined associations between age, education, and sex with cognitive performance. Norms stratified by age and education are presented. Cognitive performance showed small associations with age and education and was unrelated to sex. We provided population-based norms for Spanish tests targeting multiple cognitive domains using a large Colombian sample. These normative data may be helpful for the neuropsychological characterization of Spanish speakers from Latin America in clinical and research settings.

Indexed as

Alzheimer DiseaseAdolescentAdultAgedAged, 80 and overColombiaFemaleHumansMaleMiddle AgedNeuropsychological TestsReference ValuesRegistriesRetrospective StudiesYoung AdultAssessmentcognitionneuropsychological batterynormative dataSpanish

Identifiers

PMID31230490
PMCPMC6926163
OpenAlexW2952289547

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.