Evidence map›Paper›PMID 31232620›Full record

ArticleExpert review of proteomics2019

The role of proteomics in assessing beta-cell dysfunction and death in type 1 diabetes.

Ernesto S Nakayasu, Wei-Jun Qian, Carmella Evans-Molina, Raghavendra G Mirmira, Decio L Eizirik, Thomas O Metz

Open access · greenAbstract read
In one paragraph

Article in Expert review of proteomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Ernesto S Nakayasua Biological Sciences Division , Pacific Northwest National Laboratory , Richland , WA , USA.ORCID 0000-0002-4056-2695
Wei-Jun Qiana Biological Sciences Division , Pacific Northwest National Laboratory , Richland , WA , USA.ORCID 0000-0002-5393-2827
Carmella Evans-Molinab Center for Diabetes and Metabolic Diseases, Herman B. Wells Center for Pediatric Research, Department of Pediatrics , Indiana University School of Medicine , Indianapolis , IN , USA.
Raghavendra G Mirmirab Center for Diabetes and Metabolic Diseases, Herman B. Wells Center for Pediatric Research, Department of Pediatrics , Indiana University School of Medicine , Indianapolis , IN , USA.
Decio L Eizirikc ULB Center for Diabetes Research, Medical Faculty , Université Libre de Bruxelles , Brussels , Belgium.ORCID 0000-0003-2453-5889
Thomas O Metza Biological Sciences Division , Pacific Northwest National Laboratory , Richland , WA , USA.ORCID 0000-0001-6049-3968
Pacific Northwest National Laboratory · USIndiana University School of MedicineUniversité Libre de Bruxelles · BE

Funding

Translation CoreP30DK097512 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Carmella Evans-Molina · 2015 to 2026
$17.4M
Transcriptional Mechanisms Governing Beta Cell DifferentiationR01DK060581 · NIDDK · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Raghavendra G Mirmira · 2002 to 2026
$8.5M
Validation of small molecule 12-lipoxygenase inhibitors in metabolic diseaseR01DK105588 · NIDDK · UNIVERSITY OF CHICAGO · PI KULKARNI, ROHIT N., MIRMIRA, RAGHAVENDRA G · 2015 to 2024
$5.5M
Mechanisms of Beta Cell Function in Health and DiseaseR01DK093954 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI EVANS-MOLINA, CARMELLA · 2011 to 2019
$3.5M
Regulatory Networks and Biomarkers of Beta-cell Dysfunction and ApoptosisUC4DK104167 · NIDDK · BATTELLE PACIFIC NORTHWEST LABORATORIES · PI KULKARNI, ROHIT N., MATHEWS, CLAYTON E · 2014 to 2016
$2.7M
Biomarkers Of Beta Cell Stress In Type 1 Diabetes (BetaMarker)UC4DK104166 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI EIZIRIK, DECIO LAKS, EVANS-MOLINA, CARMELLA · 2014 to 2014
$2.4M
Serum protein biomarkers for predicting type 1 diabetesDP3DK110844 · NIDDK · BATTELLE PACIFIC NORTHWEST LABORATORIES · PI QIAN, WEI-JUN · 2016 to 2016
$1.8M
Regulation of Calcium Homeostasis in the Pancreatic Beta CellI01BX001733 · VA · RLR VA MEDICAL CENTER · PI Carmella Evans-Molina · 2013 to 2026
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BLRD VA I01 BX001733NIDDK NIH HHS DP3 DK110844NIDDK NIH HHS P30 DK097512NIDDK NIH HHS R01 DK060581NIDDK NIH HHS R01 DK093954NIDDK NIH HHS R01 DK105588NIDDK NIH HHS UC4 DK104166NIDDK NIH HHS UC4 DK104167
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diabetes Mellitus, Type 1HumansInsulin-Secreting CellsMass SpectrometryProteomicsbeta cell dysfunction and deathneoantigenstype 1 diabetes

Identifiers

PMID31232620
PMCPMC6628911
OpenAlexW2953474432

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.