Evidence map›Paper›PMID 31233100›Full record

ReviewCardiovascular research2019

Frontiers in positron emission tomography imaging of the vulnerable atherosclerotic plaque.

Mark G MacAskill, David E Newby, Adriana A S Tavares

Abstract readReview
In one paragraph

Review in Cardiovascular research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Scientific reports · 2023
    Article
  8. Feasibility of In Vivo Imaging of Fibroblast Activation Protein in Human Arterial Walls.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  9. Review
  10. Article
  11. Review
  12. Atherosclerosis Imaging withDiagnostics (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mark G MacAskillUniversity/BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
David E NewbyUniversity/BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
Adriana A S TavaresUniversity/BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.

Funding

British Heart Foundation CH/09/002British Heart Foundation PG/17/83/33370British Heart Foundation RE/18/5/34216British Heart Foundation RG/16/10/32375Medical Research Council G0701127Wellcome Trust
6 · The paper itself

Abstract

Rupture of vulnerable atherosclerotic plaques leading to an atherothrombotic event is the primary driver of myocardial infarction and stroke. The ability to detect non-invasively the presence and evolution of vulnerable plaques could have a huge impact on the future identification and management of atherosclerotic cardiovascular disease. Positron emission tomography (PET) imaging with an appropriate radiotracer has the potential to achieve this goal. This review will discuss the biological hallmarks of plaque vulnerability before going on to evaluate and to present PET imaging approaches which target these processes. The focus of this review will be on techniques beyond [18F]FDG imaging, some of which are clinically advanced, and others which are on the horizon. As inflammation is the primary driving force behind atherosclerotic plaque development, we will predominantly focus on approaches which either directly, or indirectly, target this process.

Indexed as

Molecular ImagingPlaque, AtheroscleroticPositron-Emission TomographyApoptosisArteriesAtherosclerosisCell HypoxiaHemorrhageHumansInflammation MediatorsNeovascularization, PathologicPredictive Value of TestsPrognosisReproducibility of ResultsRupture, SpontaneousInflammation MediatorsAtherosclerosisInflammationPETVulnerable plaque

Identifiers

PMID31233100
PMCPMC6872971

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.