ArticleCancer research2019
Recycling Endosomes in Mature Epithelia Restrain Tumorigenic Signaling.
Open access · bronzeAbstract read
In one paragraph
Article in Cancer research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 31 citations in OpenAlex.
- AP-1B Controls Several Levels of Cell Proliferation and Differentiation in Mouse Enteroids.Biology of the cell · 2026Article
- Myosin VB is critical for progenitor cell identity and function in the intestine.Stem cell reports · 2026Article
- Acid sphingomyelinase inhibition restores RPE homeostasis and photoreceptor function in preclinical Stargardt macular degeneration models.bioRxiv : the preprint server for biology · 2026Article
- Rab11b is necessary for mitochondrial integrity and function in gut epithelial cells.Frontiers in cell and developmental biology · 2025Article
- Function and regulation of Rab GTPases in cancers.Cell biology and toxicology · 2024Review
- Article
- PPP1R12A is a recycling endosomal phosphatase that facilitates YAP activation.Scientific reports · 2023Article
- RAB11A and RAB11B control mitotic spindle function in intestinal epithelial progenitor cells.EMBO reports · 2023Article
- The SLITRK4-CNPY3 axis promotes liver metastasis of gastric cancer by enhancing the endocytosis and recycling of TrkB in tumour cells.Cellular oncology (Dordrecht, Netherlands) · 2023Article
- Targeting TMEM205 mediated drug resistance in ovarian clear cell carcinoma using oncolytic virus.Journal of ovarian research · 2022Article
- Article
- Myosin Vb as a tumor suppressor gene in intestinal cancer.Oncogene · 2022Article
- Rab21 in enterocytes participates in intestinal epithelium maintenance.Molecular biology of the cell · 2022Article
- RNF6 promotes the migration and invasion of breast cancer by promoting the ubiquitination and degradation of MST1.Experimental and therapeutic medicine · 2022Article
- 1,25-Dihydroxyvitamin DJournal of cellular physiology · 2021Article
- Hippo pathway: Regulation, deregulation and potential therapeutic targets in cancer.Cancer letters · 2021Review
- Rab11fip5 regulates telencephalon development via ephrinB1 recycling.Development (Cambridge, England) · 2021Article
- Review
- The Endosomal Recycling Pathway-At the Crossroads of the Cell.International journal of molecular sciences · 2020Review
- Novel genetic variants ofAmerican journal of cancer research · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors at 4 institutions in 3 countries.
Luca D'Agostino *Department of Biological Sciences, Rutgers University, Newark, New Jersey.
Yingchao Nie *Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts.ORCID 0000-0001-6151-0811
Sayantani Goswami *Department of Biological Sciences, Rutgers University, Newark, New Jersey.
Kevin TongDepartment of Genetics, Rutgers University, Piscataway, New Jersey.
Shiyan YuDepartment of Biological Sciences, Rutgers University, Newark, New Jersey.
Sheila BandyopadhyayDepartment of Biological Sciences, Rutgers University, Newark, New Jersey.
Juan FloresDepartment of Biological Sciences, Rutgers University, Newark, New Jersey.
Xiao ZhangDepartment of Biological Sciences, Rutgers University, Newark, New Jersey.ORCID 0000-0002-8213-6686
Iyshwarya BalasubramanianDepartment of Biological Sciences, Rutgers University, Newark, New Jersey.
Ivor JosephDepartment of Biological Sciences, Rutgers University, Newark, New Jersey.
Ryotaro SakamoriDepartment of Biological Sciences, Rutgers University, Newark, New Jersey.ORCID 0000-0002-1580-607X
Victoria FarrellDepartment of Biological Sciences, Rutgers University, Newark, New Jersey.
Qi LiProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts.
Chung S YangDepartment of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey.ORCID 0000-0001-6713-4837
Bin GaoDepartment of Internal Medicine, Taixing Chinese Medicine Hospital, Taixing, Jiangsu, China.
Ronaldo P FerrarisDepartment of Pharmacology, Physiology, and Neuroscience, Rutgers New Jersey Medical School, Newark, New Jersey.
Ghassan YehiaRutgers Genome Editing Core Facility, Rutgers University, New Brunswick, New Jersey.ORCID 0000-0002-9834-6012
Edward M BonderDepartment of Biological Sciences, Rutgers University, Newark, New Jersey.
James R GoldenringDepartment of Surgery, Cell and Developmental Biology, and Epithelial Center, Vanderbilt University School of Medicine, Nashville, Tennessee.ORCID 0000-0002-7833-2940
Michael P VerziDepartment of Genetics, Rutgers University, Piscataway, New Jersey.
Lanjing ZhangDepartment of Biological Sciences, Rutgers University, Newark, New Jersey.ORCID 0000-0001-5436-887X
Y Tony IpProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts. ngao@rutgers.edu tony.ip@umassmed.edu.
Nan GaoDepartment of Biological Sciences, Rutgers University, Newark, New Jersey. ngao@rutgers.edu tony.ip@umassmed.edu.
Rutgers, The State University of New Jersey · USUniversity of Massachusetts Chan Medical School · USTaixing People's Hospital · CNVanderbilt University · US
Funding
TRANSCRIPTIONAL PROFILINGP30CA072720 · NCI · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI Adam C Berger · 1997 to 2026
$94.5MTranslational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9MCOngenital Diarrhea and Enteropathy (PediCODE) Consortium and BioRepositoryRC2DK118640 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI James Richard Goldenring, Izumi Kaji · 2019 to 2026
$14.8MPILOT AND FEASIBILITY PROGRAMP30DK032520 · NIDDK · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI CZECH, MICHAEL P · 1986 to 2010
$14.6MUniversity of Massachusetts Center for Clinical and Translational ScienceUL1TR000161 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2012 to 2015
$11.0MR25 IMSD Minority Biomedical Research Support Program (MBRS)R25GM096161 · NIGMS · RUTGERS THE STATE UNIV OF NJ NEWARK · PI KOMISARUK, BARRY RICHARD · 2011 to 2020
$6.2MGenetic analysis of damage-induced intestinal stem cell division in DrosophilaR01DK083450 · NIDDK · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI IP, Y. TONY · 2010 to 2024
$4.7MTranscriptional Mechanisms of Tumor SuppressionR01CA190558 · NCI · RUTGERS, THE STATE UNIV OF N.J. · PI MICHAEL P. VERZI · 2015 to 2026
$3.6MMolecular characteristics of the apical recycling systemR01DK070856 · NIDDK · VANDERBILT UNIVERSITY · PI GOLDENRING, JAMES RICHARD · 2006 to 2014
$3.1MResearch Supplements to Promote Diversity in Health-Related ResearchR01DK119198 · NIDDK · RUTGERS THE STATE UNIV OF NJ NEWARK · PI GAO, NAN, KIELA, PAWEL R · 2019 to 2023
$1.9MEndosomal Control of Microbe-Host HomeostasisR01DK102934 · NIDDK · RUTGERS THE STATE UNIV OF NJ NEWARK · PI GAO, NAN · 2014 to 2018
$1.8MSupercomputing: Rutgers' Catalyst for Discovery at the Frontiers of MedicineS10OD012346 · OD · RBHS-NEW JERSEY MEDICAL SCHOOL · PI MICHELSON, LESLIE PAUL · 2015 to 2015
$1.7MNCATS NIH HHS UL1 TR000161NCCIH NIH HHS R01 AT010243NCI NIH HHS F32 CA235829NCI NIH HHS P30 CA072720NCI NIH HHS R01 CA190558NCI NIH HHS R21 CA178599NIDDK NIH HHS F31 DK121428NIDDK NIH HHS K01 DK085194NIDDK NIH HHS P30 DK032520NIDDK NIH HHS P30 DK058404NIDDK NIH HHS R01 DK070856NIDDK NIH HHS R01 DK083450NIDDK NIH HHS R01 DK102934NIDDK NIH HHS R01 DK119198NIDDK NIH HHS R03 DK093809NIDDK NIH HHS RC2 DK118640NIGMS NIH HHS R01 GM107457NIGMS NIH HHS R25 GM096161NIH HHS S10 OD012346
Abstract
The effects of polarized membrane trafficking in mature epithelial tissue on cell growth and cancer progression have not been fully explored
Indexed as
Adenomatous Polyposis Coli ProteinAnimalsAnimals, Genetically ModifiedColorectal NeoplasmsEndosomesEpithelial CellsHippo Signaling PathwayHumansMice, KnockoutProtein Serine-Threonine Kinasesrab11 GTP-Binding Proteinsrab GTP-Binding ProteinsStem CellsAdenomatous Polyposis Coli Proteinadenomatous polyposis coli protein, mouseProtein Serine-Threonine Kinasesrab11 GTP-Binding Proteinsrab GTP-Binding Proteins
Identifiers
What Socratic holds
Textmetadata
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Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.