Evidence map›Paper›PMID 31246891›Full record

ArticleJournal of hypertension2019

Sex differences in masked hypertension: the Coronary Artery Risk Development in Young Adults study.

Daniel N Pugliese, John N Booth, Luqin Deng, D Edmund Anstey, Natalie A Bello, Byron C Jaeger, James M Shikany, Donald Lloyd-Jones, Cora E Lewis, Joseph E Schwartz and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of hypertension, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Blood pressure and vascular function response to maximal graded exercise tests in young men with masked hypertension.American journal of physiology. Regulatory, integrative and comparative physiology · 2025
    Article
  2. Review
  3. Sex and gender differences in cognitive resilience to aging and Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Review
  4. Psychological resources and incident hypertension in the coronary artery risk development in young adults (CARDIA) study.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Daniel N PuglieseDepartment of Medicine, Columbia University, New York, New York.
John N BoothDepartment of Epidemiology.
Luqin DengDepartment of Epidemiology.
D Edmund AnsteyDepartment of Medicine, Columbia University, New York, New York.
Natalie A BelloDepartment of Medicine, Columbia University, New York, New York.
Byron C JaegerDepartment of Biostatistics.
James M ShikanyDivision of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Donald Lloyd-JonesDepartment of Preventive Medicine, Northwestern University, Chicago, Illinois.
Cora E LewisDepartment of Epidemiology.
Joseph E SchwartzDepartment of Medicine, Columbia University, New York, New York.
Paul MuntnerDepartment of Epidemiology.
Daichi ShimboDepartment of Medicine, Columbia University, New York, New York.
Columbia University · USNorthwestern University · USStony Brook University · USUniversity of Alabama at Birmingham · US

Funding

POSTDOCTORAL TRAINING IN CARDIOVASCULAR DISEASET32HL007854 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Marwah Abdalla, Michael Argenziano · 1996 to 2026
$14.7M
Incorporation of a Hypertension Working Group into the Jackson Heart StudyR01HL117323 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA E, OGEDEGBE, OLUGBENGA G. · 2013 to 2024
$7.2M
Blood Pressure Measurement and Hypertension in PregnancyK23HL136853 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BELLO, NATALIE A · 2018 to 2022
$948k
Midcareer Investigator Award in Patient-Oriented Research in Human HypertensionK24HL125704 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHIMBO, DAICHI · 2015 to 2019
$573k
NHLBI NIH HHS HHSN268201800003INHLBI NIH HHS HHSN268201800004INHLBI NIH HHS HHSN268201800005INHLBI NIH HHS HHSN268201800006INHLBI NIH HHS HHSN268201800007INHLBI NIH HHS K23 HL136853NHLBI NIH HHS K24 HL125704NHLBI NIH HHS R01 HL117323NHLBI NIH HHS T32 HL007854
6 · The paper itself

Abstract

objectiveTo evaluate the association of sex with masked hypertension, defined by out-of-clinic hypertension based on ambulatory blood pressure monitoring (ABPM) among adults without hypertension based on blood pressure (BP) measured in the clinic, after adjusting for potential confounders.

methodsWe evaluated sex differences in the prevalence of masked hypertension and the difference between awake, or alternatively 24-h, ambulatory BP and clinic BP using multivariable adjusted models among 658 participants who underwent 24-h ABPM and had clinic SBP/DBP less than 140/90 mmHg during the Year 30 Exam of the Coronary Artery Risk Development in Young Adults study.

resultsThe mean age ± standard deviation (SD) of the participants was 54.8 ± 3.7 years, 58.4% were women, and 58.2% were black. The prevalence of any masked hypertension was 37.5% among women and 60.6% among men. In a model including adjustment for demographics, cardiovascular risk factors, antihypertensive medication, and clinic BP, the prevalence ratios (95% confidence intervals) comparing men versus women were 1.39 (1.18-1.63) for any masked hypertension, and 1.60 (1.28-1.99), 1.71 (1.36-2.15), and 1.40 (1.13-1.73) for masked awake, 24-h and asleep hypertension, respectively. In a fully adjusted model, the differences between mean awake ambulatory BP and clinic BP were 2.75 [standard error (SE) 0.92] mmHg higher for SBP and 3.61 (SE 0.58) mmHg higher for DBP among men compared with women.

conclusionThe prevalence of masked hypertension on ABPM was high in both men and women. Male sex was an independent predictor of masked hypertension.

Indexed as

Sex FactorsBlood Pressure Monitoring, AmbulatoryFemaleHealth SurveysHumansMaleMasked HypertensionMiddle Aged

Identifiers

PMID31246891
PMCPMC7006727
OpenAlexW2954203762

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.