Evidence map›Paper›PMID 31247940›Full record

ArticleJournal of clinical medicine2019

Effects of Fructose or Glucose on Circulating ApoCIII and Triglyceride and Cholesterol Content of Lipoprotein Subfractions in Humans.

Bettina Hieronimus, Steven C Griffen, Nancy L Keim, Andrew A Bremer, Lars Berglund, Katsuyuki Nakajima, Peter J Havel, Kimber L Stanhope

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Sugar and Dyslipidemia: A Double-Hit, Perfect Storm.Journal of clinical medicine · 2023
    Review
  9. Article
  10. Article
  11. Fructose and the Liver.International journal of molecular sciences · 2021
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Dietary Impact on Postprandial Lipemia.Frontiers in endocrinology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Bettina HieronimusDepartment of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.ORCID 0000-0001-7494-4707
Steven C GriffenDepartment of Internal Medicine, School of Medicine, University of California, Davis, Sacramento, CA 95817, USA.
Nancy L KeimUnited States Department of Agriculture, Western Human Nutrition Research Center, Davis, CA 95616, USA.
Andrew A BremerDepartment of Pediatrics, School of Medicine, University of California, Davis, Sacramento, CA 95817, USA.
Lars BerglundDepartment of Internal Medicine, School of Medicine, University of California, Davis, Sacramento, CA 95817, USA.
Katsuyuki NakajimaDepartment of Clinical Laboratory Medicine, Gunma University Graduate School of Medicine, Maebashi, Gunma 371-8510, Japan.
Peter J HavelDepartment of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.
Kimber L StanhopeDepartment of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, CA 95616, USA. klstanhope@ucdavis.edu.ORCID 0000-0002-2474-0914
University of California, Davis · USKanazawa Medical University · JPUnited States Department of Agriculture · US

Funding

UC DAVIS CLINICAL AND TRANSLATIONAL SCIENCE CENTER: BPCAUL1RR024146 · NCRR · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BERGLUND, LARS F · 2006 to 2011
$27.0M
Deutsche Forschungsgemeinschaft HI 2113/1-1National Center for Research Resources UL1 RR024146National Institutes of Health R01 HL-075675
6 · The paper itself

Abstract

ApoCIII and triglyceride (TG)-rich lipoproteins (TRL), particularly, large TG-rich lipoproteins particles, have been described as important mediators of cardiovascular disease (CVD) risk. The effects of sustained consumption of dietary fructose compared with those of sustained glucose consumption on circulating apoCIII and large TRL particles have not been reported. We measured apoCIII concentrations and the TG and cholesterol content of lipoprotein subfractions separated by size in fasting and postprandial plasma collected from men and women (age: 54 ± 8 years) before and after they consumed glucose- or fructose-sweetened beverages for 10 weeks. The subjects consuming fructose exhibited higher fasting and postprandial plasma apoCIII concentrations than the subjects consuming glucose (

Indexed as

atherosclerosis risk factorsclinical studiesLDLlipid and lipoprotein metabolismlipoprotein fractionsnutrition/carbohydratessugarTG-rich lipoproteins

Identifiers

PMID31247940
PMCPMC6678650
OpenAlexW2953749220

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.