ArticleHaematologica2020
Glutathione peroxidase 4 and vitamin E control reticulocyte maturation, stress erythropoiesis and iron homeostasis.
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In one paragraph
Article in Haematologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 83 citations in OpenAlex.
- Redox Modulation of Erythropoiesis by Selenoproteins.Biological trace element research · 2026Review
- Metabolic Functions and Mechanisms of Selenium, Selenocysteine, and GPX4 Mediated Immune Regulation Through Autophagy in Solid Tumors.Food science & nutrition · 2025Review
- TP53 Expression Status Alters Hemoglobinization and Ferroptosis Sensitivity in K-562 Cells.International journal of molecular sciences · 2025Article
- Rehmanniae Radix Praeparata in Blood Deficiency Syndrome: UPLC-Q-TOF-MS Profiling, Network Pharmacology, and PI3K-AKT Activation.International journal of molecular sciences · 2025Article
- Human serum albumin or polyvinyl alcohol can only partially replace human plasma during in vitro red cell production from PBMC.Scientific reports · 2025Article
- Cell death signaling in human erythron: erythrocytes lose the complexity of cell death machinery upon maturation.Apoptosis : an international journal on programmed cell death · 2025Review
- Selenoprotein-mediated redox regulation shapes the cell fate of HSCs and mature lineages.Blood · 2025Article
- The Impact of Sodium Selenite and Seleno-L-Methionine on Stress Erythropoiesis in a Murine Model of Hemolytic Anemia.The Journal of nutrition · 2025Article
- Hematopoietic effects of Fufang E'jiao Jiang revealed by microbiome, metabolome and transcriptome analyses: a multi-omics strategy.Frontiers in immunology · 2025Article
- Eryptosis in renal anemia: mechanisms, clinical implications, and therapeutic targeting.Frontiers in pharmacology · 2025Review
- The emerging role and therapeutical implications of ferroptosis in wound healing.Burns & trauma · 2025Review
- Evaluation of urine glutathione peroxidase 4 in cats with chronic kidney disease.Frontiers in veterinary science · 2025Article
- Interplay Between Metabolic Pathways and Increased Oxidative Stress in Human Red Blood Cells.Cells · 2024Review
- Human-augmented large language model-driven selection of glutathione peroxidase 4 as a candidate blood transcriptional biomarker for circulating erythroid cells.Scientific reports · 2024Article
- Modulation of Antioxidant Enzyme Expression of In Vitro Culture-Derived Reticulocytes.Antioxidants (Basel, Switzerland) · 2024Article
- Vitamin E and GPX4 cooperatively protect treg cells from ferroptosis and alleviate intestinal inflammatory damage in necrotizing enterocolitis.Redox biology · 2024Article
- Ferroptosis in health and disease.Redox biology · 2024Review
- Identification of three mechanistic pathways for iron-deficient heart failure.European heart journal · 2024Review
- Emerging role of glutathione peroxidase 4 in myeloid cell lineage development and acute myeloid leukemia.Cellular & molecular biology letters · 2024Review
- Glutathione peroxidase 4 restrains temporomandibular joint osteoarthritis progression by inhibiting ferroptosis.Journal of cellular and molecular medicine · 2024Article
Corrections and comments
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Authors and funding
24 authors at 6 institutions in 3 countries.
Sandro AltamuraDepartment of Pediatric Hematology, Oncology and Immunology - University of Heidelberg, Heidelberg, Germany.
Naidu M VegiInstitute of Experimental Cancer Research, Universitätsklinikum Ulm, Ulm, Germany.
Philipp S HoppeDepartment of Biosystems Bioscience and Engineering, ETH Zürich, Basel, Switzerland.
Timm SchroederDepartment of Biosystems Bioscience and Engineering, ETH Zürich, Basel, Switzerland.
Michaela AichlerResearch Unit Analytical Pathology, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Neuherberg, Germany.
Axel WalchResearch Unit Analytical Pathology, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Neuherberg, Germany.
Katarzyna OkreglickaInstitute of Molecular Health Sciences, ETH Zurich, Zürich, Switzerland.
Lothar HültnerInstitute of Clinical Molecular Biology and Tumor Genetics, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), München, Germany.
Manuela SchneiderInstitute for Stroke and Dementia Research (ISD), Klinikum der Universität München, München, Germany.
Camilla LadinigInstitute of Clinical Molecular Biology and Tumor Genetics, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), München, Germany.
Cornelia Kuklik-RoosInstitute of Clinical Molecular Biology and Tumor Genetics, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), München, Germany.
Josef MysliwietzInstitute of Molecular Immunology, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), München, Germany.
Dirk JanikResearch Unit Analytical Pathology, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Neuherberg, Germany.
Frauke NeffResearch Unit Analytical Pathology, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Neuherberg, Germany.
Birgit RathkolbInstitute of Molecular Animal Breeding and Biotechnology, Ludwig-Maximilians-Universität München, Genzentum, München, Germany.
Mar Tin Hrabé de AngelisInstitute of Experimental Genetics, Geman Mouse Clinic (GMC), Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Neuherberg, Germany.
Christian BuskeInstitute of Experimental Cancer Research, Universitätsklinikum Ulm, Ulm, Germany.
Ana Rita da SilvaDepartment of Pediatric Hematology, Oncology and Immunology - University of Heidelberg, Heidelberg, Germany.
Katja MuedderDepartment of Pediatric Hematology, Oncology and Immunology - University of Heidelberg, Heidelberg, Germany.
Marcus ConradInstitute of Developmental Genetics, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), Neuherberg, Germany.
Tomas GanzDepartments of Medicine and Pathology, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
Manfred KopfInstitute of Molecular Health Sciences, ETH Zurich, Zürich, Switzerland.
Martina U MuckenthalerDepartment of Pediatric Hematology, Oncology and Immunology - University of Heidelberg, Heidelberg, Germany.
Georg W BornkammInstitute of Clinical Molecular Biology and Tumor Genetics, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), München, Germany georg.bornkamm@t-online.de.
Helmholtz Zentrum München · DEETH Zurich · CHHeidelberg University · DEUniversity Hospital Ulm · DETechnical University of Munich · DEUniversity of California, Los Angeles · US
Funding
No grant is acknowledged in the PubMed record.
Abstract
Glutathione peroxidase 4 (GPX4) is unique as it is the only enzyme that can prevent detrimental lipid peroxidation
Indexed as
ErythropoiesisIronReticulocytesVitamin EAnimalsHomeostasisMicePhospholipid Hydroperoxide Glutathione PeroxidaseRabbitsglutathione peroxidase 4, mouseIronPhospholipid Hydroperoxide Glutathione PeroxidaseVitamin E
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY-NC
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.