Evidence mapPaperPMID 31269877Full record

ArticleJournal of the American Heart Association2019

Changes in the Prescription of Glucose-Lowering Medications in Patients With Type 2 Diabetes Mellitus After a Cardiovascular Event: A Call to Action From the DATAFILE Study.

Gian Paolo Fadini, Vera Frison, Natalino Simioni, Annunziata Lapolla, Adriano Gatti, Antonio Carlo Bossi, Andrea Del Buono, Paolo Fornengo, Lucia Gottardo, Mario Laudato and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Observational
  2. Review
  3. Glucagon-Like Peptide 1 Receptor Agonist Usage in Type 2 Diabetes in Primary Care for the UK and Beyond: A Narrative Review.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2021
    Review
  4. Review
  5. Observational
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 1 country.

Gian Paolo Fadini1 Department of Medicine University of Padova Italy.
Vera Frison2 Diabetology Service ULSS6 Cittadella Italy.
Natalino Simioni2 Diabetology Service ULSS6 Cittadella Italy.
Annunziata Lapolla3 Diabetology Service ULSS6 Padova Italy.
Adriano Gatti4 Diabetology Service ASL Napoli 1 Centro Napoli Italy.
Antonio Carlo Bossi5 ASST Bergamo Ovest Treviglio Italy.
Andrea Del Buono6 Diabetology Service Cellole (CE) Italy.
Paolo Fornengo7 Department of Medicine Internal Medicine 3 University Hospital of Turin Italy.
Lucia Gottardo8 Internal Medicine and Diabetology ULSS3 Venice Italy.
Mario Laudato9 Diabetology Service Caserta Italy.
Gianluca Perseghin10 Department of Medicine and Rehabilitation Policlinico di Monza and University of Milan Bicocca Monza Italy.
Enzo Bonora11 Division of Endocrinology, Diabetes and Metabolism University and Hospital Trust of Verona Verona Italy.
Angelo Avogaro1 Department of Medicine University of Padova Italy.
Azienda ULSS 9 TREVISO · ITUniversity of Padua · ITAzienda Ospedaliera Treviglio · ITOspedale SS. Annunziata · ITRegione Campania · ITUniversity of Milano-Bicocca · ITUniversity of Turin · ITUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Evidence accumulated that some glucose-lowering medications protect against cardiovascular events ( CVEs ) in patients with type 2 diabetes mellitus (T2DM) and established cardiovascular disease. The present study evaluated if and how glucose-lowering medication prescription pattern changes in T2DM after a CVE. Methods and Results DATAFILE (Diabetes Therapy After a Cardiovascular Event) was a retrospective multicenter study conducted at 12 diabetes mellitus specialist outpatient clinics in Italy. We identified T2DM patients with an incident CVE for whom a follow-up visit was available after the event. We selected control T2DM patients without an incident CVE , who were matched with cases for age, sex, known diabetes mellitus duration, baseline hemoglobin A

Indexed as

Glucagon-Like Peptide-1 Receptor AgonistsAdrenergic beta-AntagonistsAgedAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsCardiovascular DiseasesCholesterol, LDLDiabetes Mellitus, Type 2Dual Anti-Platelet TherapyFemaleGlycated HemoglobinHeart FailureHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHypoglycemic AgentsItalyAdrenergic beta-AntagonistsAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsCholesterol, LDLGlucagon-Like Peptide-1 Receptor AgonistsGlycated Hemoglobinhemoglobin A1c protein, humanHydroxymethylglutaryl-CoA Reductase InhibitorsHypoglycemic AgentsMetforminSodium-Glucose Transporter 2 InhibitorsSodium Potassium Chloride Symporter Inhibitorsappropriatenessdiabetes mellituspharmacology

Identifiers

PMID31269877
PMCPMC6662129
OpenAlexW2953431890

What Socratic holds

Texttitle and abstract
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.