ReviewJournal of ophthalmology2019
An Update on Corneal Biomechanics and Architecture in Diabetes.
Review in Journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Ferroptosis: A Novel Mechanism in Diabetic Keratopathy.Investigative ophthalmology & visual science · 2026Article
- Corneal Structural Alterations Under Chronic Hyperglycemia: Biomechanical and Densitometric Insights in Type 2 Diabetes with and Without Retinopathy.Beyoglu eye journal · 2026Article
- Evaluation of corneal densitometry using Pentacam in patients with type 2 diabetes mellitus: a controlled cross-sectional study.BMC ophthalmology · 2025Article
- Automatic Determination of Endothelial Cell Density From Donor Cornea Endothelial Cell Images.Translational vision science & technology · 2024Article
- Immune-Mediated Ocular Surface Disease in Diabetes Mellitus-Clinical Perspectives and Treatment: A Narrative Review.Biomedicines · 2024Review
- Corneal Epithelial Changes in Diabetic Patients: A Review.International journal of molecular sciences · 2024Review
- Association Between Corneal Changes and Retinal Oximetry in Diabetes Mellitus.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- Corneal and intraocular pressure changes associated to the circadian rhythms: a narrative review.International journal of ophthalmology · 2024Review
- Particular Anatomy of the Hyperopic Eye and Potential Clinical Implications.Medicina (Kaunas, Lithuania) · 2023Article
- Analysis of Corneal Deformation in Paediatric Patients Affected by Maturity Onset Diabetes of the Young Type 2.Diagnostics (Basel, Switzerland) · 2023Article
- Central Corneal Thickness and Intraocular Pressure in Women With Gestational Diabetes Mellitus.Cureus · 2023Article
- Loss of Corneal Nerves and Corneal Haze in Patients with Fuchs' Endothelial Corneal Dystrophy with the Transcription Factor 4 Gene Trinucleotide Repeat Expansion.Ophthalmology science · 2023Article
- Diabetic Retinopathy: Soluble and Imaging Ocular Biomarkers.Journal of clinical medicine · 2023Review
- Measurement of corneal biomechanical properties in diabetes mellitus using the Corvis ST.Medicine · 2022Article
- Biomechanical analysis of ocular diseases and its in vitro study methods.Biomedical engineering online · 2022Review
- Article
- Risk factors for fluctuations in corneal endothelial cell density (Review).Experimental and therapeutic medicine · 2022Review
- On the Relationship between Corneal Biomechanics, Macrostructure, and Optical Properties.Journal of imaging · 2021Article
- Ocular surface complications in diabetes: The interrelationship between insulin and enkephalin.Biochemical pharmacology · 2021Review
- Nerve influence on the metabolism of type I and type II diabetic corneal stroma: an in vitro study.Scientific reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the last decade, we have witnessed substantial progress in our understanding of corneal biomechanics and architecture. It is well known that diabetes is a systemic metabolic disease that causes chronic progressive damage in the main organs of the human body, including the eyeball. Although the main and most widely recognized ocular effect of diabetes is on the retina, the structure of the cornea (the outermost and transparent tissue of the eye) can also be affected by the poor glycemic control characterizing diabetes. The different corneal structures (epithelium, stroma, and endothelium) are affected by specific complications of diabetes. The development of new noninvasive diagnostic technologies has provided a better understanding of corneal tissue modifications. The objective of this review is to describe the advances in the knowledge of the corneal alterations that diabetes can induce.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.