PCSK9 inhibitors × all-cause mortality

SynthesisJournal of clinical lipidology

Association of baseline LDL-C with total and cardiovascular mortality in patients using proprotein convertase subtilisin-kexin type 9 inhibitors: A systematic review and meta-analysis.

Safi U Khan et al.PubMed ↗Full text ↗Publisher ↗

What moved togetherboth groups pooled, not the treatment’s effect

Correlation · may be no link

No clear link with deaths

−6%−19% to +9%

Bigger than 2 in 10 for all-cause mortality

As reported

RR 0.94, 95% CI 0.81–1.09 · the paper's word: All-cause mortality

One number in the abstract

the abstract, start to end

all-cause mortality (relative risk [RR], 0.94, 95% confidence interval [CI],

← favours treatmentfavours comparator →
could be chance
All-cause mortality
RR 0.940.81–1.09
PCSK9 inhibitorsAll-cause mortality
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9 papers cite it

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pooled ittrialcites it
Full record →Abstract, authors, funding and every citing paper · PMID 31278046