Evidence map›Paper›PMID 31280830›Full record

Trial reportIndian heart journal

Effects of home-based exercise training on functional outcomes and quality of life in patients with pulmonary hypertension: A randomized clinical trial.

Abraham Samuel Babu, Ramachandran Padmakumar, Krishnanand Nayak, Ranjan Shetty, Aswini Kumar Mohapatra, Arun G Maiya

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Effectiveness and safety of home-basedEuropean respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  3. Pooled it
  4. Exercise-based rehabilitation programmes for pulmonary hypertension.The Cochrane database of systematic reviews · 2023
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Abraham Samuel BabuDepartment of Physiotherapy, School of Allied Health Sciences, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India.
Ramachandran PadmakumarDepartment of Cardiology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India. Electronic address: docpk.ramachandran@gmail.com.
Krishnanand NayakDepartment of Cardiovascular Technology, School of Allied Health Sciences, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India.
Ranjan ShettyDepartment of Cardiology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India; Department of Cardiology, Manipal Hospital, Hal Airport Road, Bengaluru, 560017, Karnataka, India.
Aswini Kumar MohapatraDepartment of Pulmonary Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India.
Arun G MaiyaDepartment of Physiotherapy, School of Allied Health Sciences, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe objective of this study was to assess the effects of home-based exercise training (HBET) on function and quality of life (QoL) in patients with pulmonary hypertension (PH).

methodsA prospective, nonblinded, randomized clinical trial was carried out on 84 medically stable patients with PH belonging to any functional class or etiology and of either sex. Patients were randomized to either standard care or HBET. Both groups also received education using the Pulmonary Hypertension Manual (PulHMan). Outcomes included functional capacity from 6-min walk distance (6MWD), QoL using the Medical Outcomes Survey Short Form - 36, functional class (FC), and right heart indices (right ventricular systolic pressure [RVSP] and tricuspid annular plane systolic excursion [TAPSE]) and were assessed at entry and after 12 weeks.

resultsHBET improved 6MWD by 48.5 m and 13 m in the experimental and control groups, respectively (p < 0.001). QoL showed statistical improvements after HBET between the groups for the physical and mental components and for the various subdomains (except body pain). Furthermore, FC improved by one grade with HBET (p < 0.001).

conclusionHBET program improved functional capacity, QoL, and FC in patients with PH.

Indexed as

ExerciseExercise ToleranceHome Care ServicesQuality of LifeFemaleHumansHypertension, PulmonaryMaleMiddle AgedProspective StudiesExercise trainingPulmonary arterial hypertensionQuality of lifeRehabilitationSix-minute walk distance

Identifiers

PMID31280830
PMCPMC6620412

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.